Diagnosis of invasive aspergillus tracheobronchitis facilitated by endobronchial ultrasound-guided transbronchial needle aspiration: a case report.

Journal of Medical Case Reports
Roberto F CasalGeorgie A Eapen

Abstract

Invasive pulmonary aspergillosis is the most common form of infection by Aspergillus species among immunocompromised patients. Although this infection frequently involves the lung parenchyma, it is unusual to find it limited to the tracheobronchial tree, a condition known as invasive aspergillus tracheobronchitis. A 65 year-old Hispanic man from Bolivia with a history of chronic lymphocytic leukemia developed cough and malaise eight months after having an allogenic stem cell transplant. A computed tomography of the chest revealed an area of diffuse soft tissue thickening around the left main stem bronchus, which was intensely fluorodeoxyglucose-avid on positron emission tomography scanning. An initial bronchoscopic exam revealed circumferential narrowing of the entire left main stem bronchus with necrotic and friable material on the medial wall. Neither aspirates from this necrotic area nor bronchial washing were diagnostic. A second bronchoscopy with endobronchial ultrasound evidenced a soft tissue thickening on the medial aspect of the left main stem bronchus underlying the area of necrosis visible endoluminally. Endobronchial ultrasound-guided transbronchial needle aspiration performed in this area revealed multiple fungal e...Continue Reading

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Citations

Mar 6, 2012·Current Opinion in Pulmonary Medicine·John H Reynolds, Arpan K Banerjee
Dec 24, 2011·TheScientificWorldJournal·Rafal Krenke, Elzbieta M Grabczak
Aug 20, 2010·Medical Mycology·Arunaloke ChakrabartiM R Shivaprakash
Feb 18, 2016·Endoscopic Ultrasound·Eduardo Rodrigues-PintoGuilherme Macedo
Jun 28, 2011·Revista iberoamericana de micología·Cristina López García-GalloPiedad Ussetti-Gil
Nov 8, 2014·Medical Mycology Case Reports·Peter RummensVincent Ninane
May 23, 2015·International Journal of Rheumatic Diseases·Warren Fong, Ying Ying Chua
Aug 1, 2016·Annales de pathologie·Hajar SlimaniJamal-Eddine Bourkadi
Jul 23, 2016·Chest·Tanmay S PanchabhaiAtul C Mehta
Sep 19, 2017·Current Opinion in Infectious Diseases·Abby DouglasMonica Slavin

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Methods Mentioned

BETA
biopsies

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