PMID: 45874Jan 1, 1975

Diagnosis of plasma cell myeloma

American Family Physician
M W PasmantierR T Silver

Abstract

Diagnosis of myeloma depends on identification of malignant plasma cells and the product of these cells, a monoclonal immunoprotein. Of the clinical manifestations of plasma cell myeloma, skeletal pain and anemia are two of the more common. Unexplained anemia and osteoporosis noted in the elderly should suggest the possibility of myeloma; this combination of symptoms certainly warrants obtaining a protein electrophoresis. Hypercalcemia and renal insufficiency are frequent sequelae of myeloma.

References

Jul 1, 1983·Journal of Clinical Immunology·C D PlatsoucasB D Clarkson
Feb 1, 1991·Immunology and Cell Biology·V Ruszala-MallonB S Wang
May 1, 1989·Postgraduate Medical Journal·R A Coward
Mar 1, 1983·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·H M LazarusM C Smith
Aug 28, 2012·Advances in Chronic Kidney Disease·Esftathios KastritisJoan Bladé
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Related Concepts

Electrophoresis, Paper
Immunoelectrophoresis
Kidney Failure
Malignant Bone Neoplasm
Proteinuria
Serum Proteins
Milk-Alkali Syndrome
Blood Coagulation Disorders
Renal Insufficiency
Uremia

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