Diagnosis of schizophrenia: reliability of an operationalized approach to 'praecox-feeling'

Psychopathology
Gabor S UngvariHelen F K Chiu

Abstract

H.C. Rumke coined the term 'praecox-feeling' to denote a specific unease experienced by the clinician reflecting the 'impossibility of empathy' and 'lack of exchange of affect' that has been reported to occur early on when examining schizophrenia patients. There is ample evidence that praecox-feeling is still relevant in modern clinical practice. This study examined the reliability of operationalized praecox-feeling against the background of modern diagnostic criteria and assessment methods. 102 consecutively admitted patients (37 with a diagnosis of schizophrenia) were interviewed within 2 days of their admission to a university-affiliated acute psychiatric unit. This initial interview was observed by 5 psychiatrists who had never seen the patients before. The interview lasted 2 min and consisted of standard, non-specific questions. The observing clinicians independently rated the absence or presence of praecox-feeling for each patient at 30 s and 2 min after encountering the patients. A sixth psychiatrist then examined the patients using the SCID-DSM-IV and all available information to reach a best estimate DSM-IV diagnosis. Measured against a research diagnosis, praecox-feeling had unsatisfactory sensitivity, specificity, po...Continue Reading

Citations

Nov 27, 2018·Schizophrenia Bulletin·Tudi GozéMichel Cermolacce
Dec 3, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Derek K TracySukhwinder S Shergill
Mar 23, 2021·Frontiers in Psychiatry·Marcin MoskalewiczTudi Gozé
Nov 1, 2018·Psychopathology·Mauro Pallagrosi, Laura Fonzi
Sep 4, 2020·Psychopathology·Laura FonziMauro Pallagrosi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.