Diagnosis of systemic-onset juvenile idiopathic arthritis after treatment for presumed Kawasaki disease

The Journal of Pediatrics
Siwen DongPreeti Jaggi

Abstract

To estimate the incidence of systemic-onset juvenile idiopathic arthritis (SoJIA) within 6 months after treatment for presumed Kawasaki disease (KD) (presumed patients with KD with subsequent diagnosis of SoJIA [pKD/SoJIA]) and describe presentation differences from sole KD. We identified patients treated for KD at Nationwide Children's Hospital and from the Pediatric Health Information System from 2009-2013. We then identified the subset of children, pKD/SoJIA, who received an International Classification of Diseases, Ninth Revision code for SoJIA and had it listed at least once 3 months after and within 6 months after KD diagnosis. Demographic characteristics, readmission rates, treatments, and complications were noted. A literature review was also performed to identify clinical, laboratory, and echocardiographic data of previously documented patients with KD later diagnosed with SoJIA. There were 6745 total treated patients with KD in the Pediatric Health Information System database during the study period; 10 patients were identified to have pKD/SoJIA (0.2% of cohort). Those with pKD/SoJIA were predominantly Caucasian compared with patients with KD (90% and 46.8%, respectively; P=.003). Macrophage activation syndrome was mo...Continue Reading

References

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Citations

Jun 28, 2016·Clinical and Experimental Immunology·T HaraS Yamasaki
Apr 7, 2017·Journal of the Pediatric Infectious Diseases Society·Preeti JaggiKaren Texter
Jun 27, 2018·Journal of Paediatrics and Child Health·Andreia MartinsCatarina Gouveia
Mar 23, 2020·Clinical Reviews in Allergy & Immunology·Rajni KumrahSurjit Singh
Nov 15, 2020·Immunity, Inflammation and Disease·Han NieWeimin Zhou
Nov 30, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Marimar Saez-de-OcarizMarco Antonio Yamazaki-Nakashimada

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