Diagnosis of vertebral fractures in children: is a simplified algorithm-based qualitative technique reliable?

Pediatric Radiology
E AdiotomreA C Offiah

Abstract

Identification of osteoporotic vertebral fractures allows treatment opportunity reducing future risk. There is no agreed standardised method for diagnosing paediatric vertebral fractures. To evaluate the precision of a modified adult algorithm-based qualitative (ABQ) technique, applicable to children with primary or secondary osteoporosis. Three radiologists independently assessed lateral spine radiographs of 50 children with suspected reduction in bone mineral density using a modified ABQ scoring system and following simplification to include only clinically relevant parameters, a simplified ABQ score. A final consensus of all observers using simplified ABQ was performed as a reference standard for fracture characterisation. Kappa was calculated for interobserver agreement of the components of both scoring systems and intraobserver agreement of simplified ABQ based on a second read of 29 randomly selected images. Interobserver Kappa for modified ABQ scoring for fracture detection, severity and shape ranged from 0.34 to 0.49 Kappa for abnormal endplate and position assessment was 0.27 to 0.38. Inter- and intraobserver Kappa for simplified ABQ scoring for fracture detection and grade ranged from 0.37 to 0.46 and 0.45 to 0.56, re...Continue Reading

References

Sep 1, 1993·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H K GenantM C Nevitt
Mar 1, 1996·Bone·R D Wasnich
Nov 3, 1998·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M TakadaH K Genant
Apr 9, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G JiangL Ferrar
May 4, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·L FerrarR Eastell
Sep 21, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·John T Schousboe, C Rowan Debold
Oct 31, 2007·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lynne FerrarRichard Eastell
Dec 15, 2007·European Journal of Radiology·Giuseppe GuglielmiFrancesco Palmieri
Dec 17, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T FuerstB H Mitlak
Feb 7, 2009·Joint, Bone, Spine : Revue Du Rhumatisme·Franck GradosPatrice Fardellone
Feb 13, 2009·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jacqueline HaltonUNKNOWN Canadian STOPP Consortium
Jun 10, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B BuehringN Binkley
Apr 15, 2010·Arthritis Care & Research·A M HuberUNKNOWN Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) Consortium
Jan 29, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Y M KimM L Bouxsein
Mar 25, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M G RobertsJ E Adams
Apr 16, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J FeberUNKNOWN Canadian STOPP Consortium
Dec 16, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J Sanfélix-GenovésM Vega-Martínez
Jun 23, 2012·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·F KoerberO Semler
Dec 11, 2013·Pediatric Radiology·Kerry SiminoskiUNKNOWN Canadian STOPP Consortium
Feb 20, 2015·Calcified Tissue International·D DiacintiS Minisola
Apr 2, 2015·Pediatric Radiology·Jacob L JaremkoUNKNOWN Canadian STOPP Consortium National Pediatric Bone Health Working Group
Apr 17, 2015·Archives of Disease in Childhood·T J Cole

❮ Previous
Next ❯

Citations

Sep 20, 2016·The Journal of Pediatrics·Andreas KyriakouS Faisal Ahmed
Nov 14, 2018·Pediatric Radiology·Fawaz F Alqahtani, Amaka C Offiah

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Software Mentioned

Genant
ABQ

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Radiology
V A Herss NielsenB J Riis
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
G JiangL Ferrar
© 2022 Meta ULC. All rights reserved