PMID: 9436546Jan 22, 1998Paper

Diagnosis of visceral pleural invasion in resected lung cancer using a jet stream of saline solution

The Annals of Thoracic Surgery
Y IchinoseY Katsuda

Abstract

Visceral pleural invasion by the tumor is an important prognostic factor in patients undergoing resection for lung cancer. We developed a method to detect more accurately the presence of visceral pleural invasion in resected lung cancer. The surface of the visceral pleura over 90 resected peripheral tumors was irrigated twice with a jet stream of saline solution using a 20-mL syringe with a 21-gauge needle, and then the fluid, which contained desquamated cells, was collected for cytologic analysis. When cancer cells were found in the collected fluid, the tumor was judged to have invaded the visceral pleura. Thirty-eight (42%) resected tumors were identified as having visceral pleural invasion either by our new method or by pathologic examination. Twenty-four cases were detected by the jet stream of saline method alone, 5 by pathologic examination alone, and 9 by both techniques. The sensitivity and accuracy of the two approaches in the diagnosis of visceral pleural invasion were 87% and 94%, respectively, for our new method, and 37% and 73%, respectively, for pathologic examination (p < 0.0001). Furthermore, among 38 patients who had a tumor demonstrating visceral pleural invasion, 5 (13%) and 9 (24%) patients, respectively, ha...Continue Reading

Citations

May 23, 2002·The Annals of Thoracic Surgery·Yushi SaitoYoshitaka Fujii
Aug 19, 2014·Revue de pneumologie clinique·M RiquetF Le Pimpec Barthes
Nov 27, 2009·The Journal of Thoracic and Cardiovascular Surgery·Eric LimUNKNOWN International Pleural Lavage Cytology Collaborators
Jun 3, 2004·The Journal of Thoracic and Cardiovascular Surgery·Riichiroh MaruyamaYukito Ichinose
Apr 20, 2001·The Annals of Thoracic Surgery·D Manac'hC Danel
Mar 20, 2003·The Annals of Thoracic Surgery·Noriyoshi SawabataUNKNOWN Thoracic Surgery Study Group of Osaka University
Dec 23, 2004·Advances in Anatomic Pathology·Kelly J Butnor, Kumarasen Cooper
Oct 27, 2005·The Annals of Pharmacotherapy·Margaret M Charpentier
Jul 10, 2007·Archives of Pathology & Laboratory Medicine·Douglas B Flieder

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.