Diagnosis, treatment and long-term outcome of autoimmune pancreatitis in Sweden

Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Miroslav VujasinovicJ Matthias Löhr

Abstract

Autoimmune pancreatitis (AIP) is a pancreatic inflammatory process characterized by a strong inflammatory cell infiltration and two histopathologically distinct subtypes: type 1 and type 2. Diagnosis is often challenging and requires a combination of clinical, laboratory and imaging data. AIP can mimic pancreatic tumours leading to unnecessary resections if not correctly diagnosed. Short- and long-term outcomes of AIP have been poorly investigated so far and no large series have been previously reported from Sweden. A single-centre, retrospective, cohort study of patients with histologically confirmed or highly probable diagnosis of AIP according to ICDC criteria. Demographic, clinical and radiological characteristics, type of treatment and its outcomes were collected and analysed. Seventy-one patients with AIP (87% with type 1), were evaluated at Karolinska University Hospital between 2004 and 2018; 49% males, mean age 49 years (range 44-53). Among them, 28% were histologically confirmed, 35% presented with jaundice, 22% with acute pancreatitis, 39% had non-specific symptoms such as weight loss or abdominal pain, 84% showed other organ involvement (OOI). Radiologically, 76% showed a focal pancreatic enlargement, 27% diffuse en...Continue Reading

Citations

Feb 20, 2019·Journal of Clinical Medicine·Miroslav VujasinovicJ-Matthias Löhr
Jun 12, 2019·International Journal of Molecular Sciences·Pedro Silva-VazJosé Guilherme Tralhão
Mar 21, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·R ValenteJ-M Löhr
May 14, 2020·United European Gastroenterology Journal·Luca BarresiUNKNOWN Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO), Italian Association for the Study of the Pancre
Sep 12, 2020·World Journal of Clinical Cases·Mario Pelaez-LunaLuis Uscanga-Domínguez
Feb 8, 2020·Journal of Clinical Medicine·Sara NikolicMiroslav Vujasinovic
Jun 20, 2020·United European Gastroenterology Journal·J-Matthias LöhrUNKNOWN UEG guideline working group
Aug 28, 2020·Frontiers in Medicine·Marco LanzillottaJonas Rosendahl
Apr 4, 2021·Journal of Clinical Medicine·Johanna BackhusAlexander Kleger
Apr 6, 2021·Endocrinología, Diabetes Y Nutrición·David Males-MaldonadoSonsoles Guadalix Iglesias
Jul 20, 2021·Autoimmunity Reviews·Ammar QureshiKam A Newman
Aug 20, 2021·Scandinavian Journal of Gastroenterology·Sara NikolicMiroslav Vujasinovic
Jul 9, 2021·Journal of Internal Medicine·Marco Del ChiaroRichard D Schulick

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