Abstract
The use of I whole body scintigraphy (WBS) before I radioiodine ablation (RIA) of the post-surgical thyroid remnant in patients with papillary thyroid cancer (PTC) remains debated. The American Thyroid Association's guidelines state that WBS may be useful before RIA (rating C-expert opinion). Some institutions do not use I WBS before RIA in their routine clinical protocol. We were therefore prompted to evaluate the impact of I WBS prior to ablation of thyroid remnant in patients with PTC. We reviewed data from 152 consecutive patients with PTC who had total thyroidectomy and were referred for RIA between August 2007 and February 2009 at our institution. The group included 107 women and 45 men, 13-82 years old (mean ± SD: 45.5 ± 18.3). Three endocrinologists blinded to the results of the I WBS reviewed patients' data including sex, age, pathology, thyroglobulin (Tg) level, anti-Tg antibodies, thyroid stimulating hormone (TSH) level and ultrasound results. Each endocrinologist then returned a form with the recommended I dose for each participant, according to the following rules: 50-75 mCi (remnant ablation), 75-125 mCi (lymph nodes metastases), 150 mCi (lung metastases), and 200 mCi (bone metastases). We compared their recommend...Continue Reading
References
Oct 1, 1990·American Journal of Surgery·M P CunninghamA Fremgen
Feb 1, 1997·Cancer·F D GillilandC R Key
Jul 1, 1997·Surgical Oncology Clinics of North America·P A Treseler, O H Clark
Jun 1, 1997·Nuclear Medicine Communications·I R McDougall
Nov 10, 2001·The Journal of Clinical Endocrinology and Metabolism·A S AlzahraniA Al Haj
May 25, 2004·Nuclear Medicine Communications·Jason B CohenI Ross McDougall
Aug 3, 2004·Radiology·Hung Q DamCharles M Intenzo
May 7, 2005·Thyroid : Official Journal of the American Thyroid Association·Susanne KohlfuerstPeter Lind
Jan 27, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Muammer UrhanSusan J Mandel
Jun 19, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Edward B Silberstein
Mar 14, 2009·Thyroid : Official Journal of the American Thyroid Association·Douglas Van NostrandLeonard Wartofsky
Aug 4, 2009·Thyroid : Official Journal of the American Thyroid Association·I Ross McDougall
Sep 8, 2009·Thyroid : Official Journal of the American Thyroid Association·Richard T Kloos
Oct 29, 2009·Thyroid : Official Journal of the American Thyroid Association·UNKNOWN American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid CancerR Michael Tuttle
Dec 17, 2009·Thyroid : Official Journal of the American Thyroid Association·Douglas Van Nostrand
Feb 4, 2012·Thyroid : Official Journal of the American Thyroid Association·Ming-Kai ChenDavid W Cheng
Jul 13, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Edward B SilbersteinAlan D Waxman
Feb 23, 2013·The Journal of Clinical Endocrinology and Metabolism·Anca M AvramKa Kit Wong
May 15, 2013·Lancet·Donald S A McLeodDavid S Cooper
Jan 10, 2018·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Citations
Jun 27, 2020·Medicine·Zhi-Ying JiaFu-Cheng Ma
Oct 21, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Simran ArjaniRavi J Chokshi
Apr 2, 2021·Thyroid : Official Journal of the American Thyroid Association·Seza A GulecR Michael Tuttle
Apr 4, 2021·Diagnostics·Elizabeth J de KosterDennis Vriens
Mar 4, 2020·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Kevin J DonohoeJason A Wexler
Sep 5, 2020·Journal of Nuclear Medicine Technology·Twyla B Bartel ChairShari Moreau