Diagnostic accuracy of home sleep apnea testing using peripheral arterial tonometry for sleep apnea syndrome: protocol for a systematic review and meta-analysis v2

Masahiro IchikawaYasushi Tsujimoto


INTRODUCTION Rationale Obstructive sleep apnea (OSA) is common, and may affect approximately 1 billion adults aged 30-69 years worldwide. Of these, an estimated 425 million suffer from moderate or severe disease (1). Evidence has suggested OSA is associated with an increased incidence of hypertension, type 2 diabetes, coronary artery disease, and stroke, and early diagnosis is important to prevent these complications. The gold standard for diagnosing OSA is in-laboratory polysomnography (PSG). However, PSG is expensive, labor intensive, limited in available facilities, and can result in long waiting times(2, 3). The home sleep apnea testing (HSAT) has been developed to solve these problems. The American Academy of Sleep medicine (AASM) guidelines recommend HSAT with at least nasal pressure, chest and abdominal respiratory inductance plethysmography, and oximetry or peripheral arterial tonometry (PAT) with oximetry and actigraphy (4). Sleep studies are classified as Type I-IV, with Type Ⅲ recording two respiratory variables, oxygen saturation, and one cardiac variable. (4)A meta-analysis of HSAT suggested that HSAT alone could not be the gold standard test for OSA due to the low sensitivity and specificity. However, the meta-ana...Continue Reading

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