Diagnostic accuracy of magnetic resonance-guided prostate biopsy and template-guided transperineal saturation biopsy

Medicine
Yi ZhouHanzhong Li

Abstract

To compare the accuracy of magnetic resonance-guided prostate biopsy (MR-GPB) and template-guided transperineal prostate saturation biopsy (TTPSB).A total of 219 patients with elevated prostate-specific antigen, abnormal digital rectal examination or ultrasound findings were enrolled. All patients underwent multiparametric magnetic resonance image (mpMRI). Patients with a Prostate Imaging Reporting and Data System (PI-RADS) score of 3 to 5 underwent MR-GPB using 2 to 5 biopsy cores and then immediately underwent an 11-region TTPSB. Patients with a PI-RADS score of 1 to 2 underwent TTPSB alone. We compared the detection rates for any cancer, clinically significant prostate cancer (csPCA), and the spatial distribution of missed csPCA lesions.Among the 219 cases, 66 (30.1%) had a PI-RADS score of 1 to 2 on mpMRI. The detection rate of TTPSB in these patients was 9.1% (6/66). In total, detection rates for any cancer and csPCA were 48.9% (107/219) and 42.9% (94/219), respectively. Detection rates for any cancer (TTPSB 87/219, 39.7%; MR-GPB76/219, 34.7%, P = .161) and csPCA (TTPSB 76/219, 34.7%; MR-GPB 72/219, 32.9%, P = .636) did not significantly differ between the 2 groups. The csPCA lesions missed by MR-GPB were most commonly loc...Continue Reading

References

Oct 23, 2009·The New England Journal of Medicine·Hashim Uddin Ahmed
Sep 26, 2013·Nature Reviews. Urology·Dwayne T S ChangNathan Lawrentschuk
Dec 20, 2014·BJU International·Zhipeng MaiHanzhong Li
Jan 28, 2015·JAMA : the Journal of the American Medical Association·M Minhaj SiddiquiPeter A Pinto
Aug 13, 2015·European Urology·Anwar R PadhaniFrancesco Sanguedolce

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Methods Mentioned

BETA
biopsies
biopsy

Software Mentioned

mpMRI
GPB
MR

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