Diagnostic accuracy of MRI texture analysis for grading gliomas

Journal of Neuro-oncology
Austin DitmerAchala Vagal

Abstract

Texture analysis (TA) can quantify variations in surface intensity or patterns, including some that are imperceptible to the human visual system. The purpose of this study was to determine the diagnostic accuracy of radiomic based filtration-histogram TA to differentiate high-grade from low-grade gliomas by assessing tumor heterogeneity. Patients with a histopathological diagnosis of glioma and preoperative 3T MRI imaging were included in this retrospective study. A region of interest was manually delineated on post-contrast T1 images. TA was performed using commercially available research software. The histogram parameters including mean, standard deviation, entropy, mean of the positive pixels, skewness, and kurtosis were analyzed at spatial scaling factors ranging from 0 to 6 mm. The parameters were correlated with WHO glioma grade using Spearman correlation. Areas under the curve (AUC) were calculated using ROC curve analysis to distinguish tumor grades. Of a total of 94 patients, 14 had low-grade gliomas and 80 had high-grade gliomas. Mean, SD, MPP, entropy and kurtosis each showed significant differences between glioma grades for different spatial scaling filters. Low and high-grade gliomas were best-discriminated using m...Continue Reading

References

Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Sep 1, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Weijie ChenGillian M Newstead
Jan 10, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Manus J DonahuePeter C M van Zijl
Mar 9, 2012·The New England Journal of Medicine·Marco GerlingerCharles Swanton
Apr 3, 2013·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Balaji Ganeshan, Kenneth A Miles
May 11, 2013·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Thida WinAshley M Groves
Jan 30, 2014·Cancers·Maria-Del-Mar IndaJoan Seoane
Nov 19, 2014·Critical Reviews in Oncogenesis·Dinorah Friedmann-Morvinski
Nov 19, 2015·Radiology·Robert J GilliesHedvig Hricak
Mar 15, 2016·European Journal of Radiology·Karoline SkogenAndrès Server
Sep 17, 2017·Radiation Oncology·Bojiang ChenWeimin Li
Oct 5, 2017·Nature Reviews. Clinical Oncology·Philippe LambinSean Walsh
Aug 1, 2016·Translational Cancer Research·Radka StoyanovaAlan Pollack

❮ Previous
Next ❯

Citations

Jul 16, 2019·Clinical Nuclear Medicine·Ana María García VicenteVíctor Manuel Pérez-García
Feb 1, 2020·Journal of Periodontology·Bianca C GonçalvesSérgio Lopes
Apr 2, 2019·Contrast Media & Molecular Imaging·Xuejin OuXuelei Ma
Jul 28, 2019·EJNMMI Research·Dániel S VeresKrisztián Szigeti
May 13, 2020·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Martin KocherPhilipp Lohmann
Sep 22, 2020·The Journal of Venomous Animals and Toxins Including Tropical Diseases·Allan Felipe Fattori AlvesDiana Rodrigues de Pina
Feb 13, 2021·AJNR. American Journal of Neuroradiology·M W WagnerB B Ertl-Wagner
Mar 12, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Akira KunimatsuOsamu Abe
Mar 25, 2021·Mathematical Biosciences and Engineering : MBE·Hakan ÖzcanTahsin Saygı
Mar 19, 2020·Journal of Neuroradiology. Journal De Neuroradiologie·Elwira SzychotAnanth Shankar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.