Diagnostic Accuracy of Multiparametric Magnetic Resonance Imaging and Fusion Guided Targeted Biopsy Evaluated by Transperineal Template Saturation Prostate Biopsy for the Detection and Characterization of Prostate Cancer

The Journal of Urology
Ashkan MortezaviDaniel Eberli

Abstract

We evaluated the diagnostic accuracy of multiparametric magnetic resonance imaging and multiparametric magnetic resonance imaging/transrectal ultrasound fusion guided targeted biopsy against that of transperineal template saturation prostate biopsy to detect prostate cancer. We retrospectively analyzed the records of 415 men who consecutively presented for prostate biopsy between November 2014 and September 2016 at our tertiary care center. Multiparametric magnetic resonance imaging was performed using a 3 Tesla device without an endorectal coil, followed by transperineal template saturation prostate biopsy with the BiopSee® fusion system. Additional fusion guided targeted biopsy was done in men with a suspicious lesion on multiparametric magnetic resonance imaging, defined as Likert score 3 to 5. Any Gleason pattern 4 or greater was defined as clinically significant prostate cancer. The detection rates of multiparametric magnetic resonance imaging and fusion guided targeted biopsy were compared with the detection rate of transperineal template saturation prostate biopsy using the McNemar test. We obtained a median of 40 (range 30 to 55) and 3 (range 2 to 4) transperineal template saturation prostate biopsy and fusion guided ta...Continue Reading

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Citations

Oct 5, 2018·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Sung Han KimWeon Seo Park
Apr 26, 2019·The Cochrane Database of Systematic Reviews·Frank-Jan H DrostIvo G Schoots
Sep 18, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Yasushi NakaiKiyohide Fujimoto
Apr 19, 2020·Abdominal Radiology·Michele ScialpiStefano Signore
Jul 11, 2020·The World Journal of Men's Health·Niklas HarlandTilman Todenhöfer
Feb 24, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Daniela A FerraroIrene A Burger
Jan 27, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Irene A BurgerDaniel Eberli

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