Diagnostic and clinical outcome of neurogenic tumours in the head and neck area

ORL; Journal for Oto-rhino-laryngology and Its Related Specialties
H G KempfT Lenarz

Abstract

A retrospective analysis of diagnostic procedures and clinical outcome of patients with neurogenic tumours of the head and neck region was performed. There were 25 patients - 16 with neurinoma, 5 with neurofibroma and 4 with neurogenic sarcoma - who presented with a mass in the head and neck area. In 13 patients, the neurinoma originated from the facial nerve, 2 of them were located in the middle ear and mastoid and showed facial palsy. Four patients presented with neurofibromatosis type 1. Twenty-three patients were operated on to remove the tumorous masses. Eighteen tumours were assigned intraoperatively to a cranial nerve main trunk, whereas 7 tumours originated from small branches or showed diffuse growth in neurofibromatosis. All benign neurogenic tumours were removed totally without relapse. One of 2 auricular nerve autografts in middle-ear facial nerve neurinoma resulted in a sufficient muscle tonus of the face. Three patients with malignancies died within 12-24 months showing local recurrencies (n = 1) and/or pulmonary metastasis (n = 2). As expected, neurogenic tumours are unusual neoplasms of the head and neck regions. On the other hand, neurogenic malignancies exhibit diagnostic problems as well as uncertain chances ...Continue Reading

Citations

Jul 23, 2003·British Journal of Plastic Surgery·R J I ColvilleJ V Soames
Sep 5, 2008·Skull Base : Official Journal of North American Skull Base Society ... [et Al.]·Deb BiswasDavid Baldwin
Jun 17, 2014·Neurocirugía·Ricardo González-Orús Álvarez-MorujoBarolomé Scola Yurrita

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