Diagnostic and Prognostic Values of BMPER in Patients with Urosepsis following Ureteroscopic Lithotripsy

BioMed Research International
Chang Geng Xu, Yong Lian Guo

Abstract

The present study aims to investigate the risk factors for urosepsis and the diagnostic and prognostic values of the bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER) in patients with urosepsis following ureteroscopic lithotripsy. A total of 305 patients with unilateral ureteral obstruction caused by calculi were included in the study. Patients were divided into three groups, namely, high, medium, and low perfusion pressure groups. The serum C-reactive protein, procalcitonin, lactate (LAC), and BMPER were measured after operation. A logistic regression model was used to assess the risk factors for postoperative urosepsis. The relationships of BMPER with laboratory parameters were explored with a multiple linear regression model. Receiver operating characteristic (ROC) curves were used to diagnosis urosepsis. The cumulative incidence of the adverse events after operation was calculated and compared by log-rank test. Forty-five patients (14.8%) had an episode of urosepsis after operation. Irrigation pressure was an independent risk factor for urosepsis. LAC and sequential organ failure assessment (SOFA) were associated with BMPER after operation. The area under curve value of BMPER for urosepsis was ...Continue Reading

References

Feb 24, 2005·Current Opinion in Urology·Paramananthan Mariappan, David A Tolley
Jan 1, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·Thomas HelbingMartin Moser
May 6, 2011·Critical Care : the Official Journal of the Critical Care Forum·Jacqueline KoezeJan G Zijlstra
Oct 14, 2011·International Journal of Antimicrobial Agents·Florian M E WagenlehnerWolfgang Weidner
Jul 10, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Xinchun PiCam Patterson
May 30, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Florian M E WagenlehnerMarkus A Weigand
Sep 6, 2014·Critical Care : the Official Journal of the Critical Care Forum·Michael BehnesUrsula Hoffmann
Jan 1, 2016·Clinica Chimica Acta; International Journal of Clinical Chemistry·Suruchi SinghRaja Roy
Feb 13, 2016·Shock·Can InceUNKNOWN ADQI XIV Workgroup
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Manu Shankar-HariUNKNOWN Sepsis Definitions Task Force
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Mervyn SingerDerek C Angus
Apr 24, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Marcos MirandaEliete Bouskela
Sep 14, 2016·Intensive Care Medicine·Jens-Ulrik Jensen, Lila Bouadma
Nov 16, 2016·Current Opinion in Urology·Florian M E WagenlehnerTruls E Bjerklund Johansen
Dec 21, 2016·Inflammation·Thomas HelbingMartin Moser
Jun 10, 2017·Arteriosclerosis, Thrombosis, and Vascular Biology·Pamela LockyerXinchun Pi
Jul 20, 2017·European Urology Focus·Omer A RaheemJohn D Denstedt
Nov 19, 2017·Critical Care Clinics·Tjitske S R van EngelenTom van der Poll

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