PMID: 18432127Apr 25, 2008Paper

Diagnostic and therapeutic problems with leucocytoclastic vasculitis--case report

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
Jolanta Sawicka-PowierzaSławomir Chlabicz

Abstract

Leucocytocalstic vasculitis (LCV) is a heterogeneous group of clinical syndromes characterized by common morphological picture of necrotic changes and inflammatory infiltration of arterioles, venules and capillary walls, mainly of neutrophils with nuclear fragments. Disorders of the immunological reactions together with the development of hypersensitivity to some antigens are observed in the course of disease if the antigen cannot by identified it is called idiopathic LCV. The aim of the study was to present the case of leucocytoclastic vasculitis together with epidemiology, pathophysiology, clinical symptoms and treatment. Conclusions. A case of a 36-year-old woman with a 16-year history of symmetrical macular exanthema type changes at the area of both shins and feet, finally diagnosed with leucocytoclastic vasculitis with further development of glomerulonephritis was reported. The authors conclude that in cases of unexplained hyperergic purpura it is necessary to consider vasculitis in differential diagnosis. They underline the value of good cooperation between General Practitioner and Specialists. Fast diagnosis and early treatment implementation could prevent development of systemic complications and alleviate skin problems.

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