PMID: 3747052Sep 12, 1986Paper

Diagnostic and therapeutic technology assessment. Angelchik antireflux prosthesis

JAMA : the Journal of the American Medical Association

Abstract

In summary, the DATTA panelists felt that the Angelchik prosthesis is effective in relieving gastroesophageal reflux and that the device, along with other types of surgical procedures, is indicated when medical management has failed and when objective evidence of incompetence of the lower esophageal sphincter is present. Because the procedure is rapid and requires little dissection, it might be most useful in the elderly and high-risk patient. Notwithstanding such support from the DATTA panelists for the device's efficacy, the majority of DATTA panelists felt that concerns about the safety of the device compromise its clinical utility. Such concern arose from past reports of complications and the panelists' own experience with migration or erosion of the device. Thus, these panelists could not recommend the device's routine use. Additionally, some DATTA panelists considered the development of the Angelchik prosthesis to be unnecessary, as standard surgical techniques, eg, fundoplication, give adequate results. The improved safety statistics reported since 1982 may remove some of these reservations in the future.

Citations

Jun 1, 1994·The Annals of Thoracic Surgery·P F Crookes, T R DeMeester

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.