Diagnostic duodenal bulb biopsy in celiac disease

Endoscopy
H VogelsangG Oberhuber

Abstract

Duodenal or jejunal biopsies are needed to establish the diagnosis of celiac disease. It is widely advocated that these biopsies be taken from the distal duodenum. After finding two index cases with diagnostic biopsies taken from the duodenal bulb, we retrospectively analyzed biopsies from the descending duodenum and the duodenal bulb of 51 patients with suspected or diagnosed celiac disease. The diagnosis of celiac disease and classification of the histological changes were performed by one pathologist. In the two index cases the diagnosis of celiac disease could only be established by taking the biopsies from the duodenal bulb, and not from the descending duodenum. In the retrospective analysis the number of intraepithelial lymphocytes was on average higher, but not significantly, in the descending part of the duodenum. Most patients with celiac disease show similar mucosal changes in biopsies taken from the descending part of the duodenum and from the duodenal bulb. But in patients who have already been on a gluten-free diet in childhood and later abandoned their diet, an additional duodenal bulb biopsy should be done.

Citations

Apr 7, 2005·Digestive Diseases and Sciences·Giovanni CammarotaGiovanni Gasbarrini
Feb 1, 2011·Clinical Reviews in Allergy & Immunology·Orit RozenbergMira Barak
Feb 10, 2010·World Journal of Pediatrics : WJP·Kaushal Kishor PrasadKartar Singh
Nov 24, 2004·Gastrointestinal Endoscopy·Giovanni CammarotaGiovanni Gasbarrini
Apr 2, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Lorenzo MemeoGovind Bhagat
Nov 13, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Giovanni CammarotaAntonio Gasbarrini
Mar 1, 2013·International Immunology·Raffaella NennaMargherita Bonamico
Jan 22, 2004·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoFabio Massimo Magliocca
Jun 20, 2007·Journal of Clinical Gastroenterology·Giovanni CammarotaGiovanni Gasbarrini
Apr 30, 2005·Journal of Pediatric Gastroenterology and Nutrition·Mila HaapalahtiJorma Kokkonen
Dec 12, 2007·Journal of Gastroenterology and Hepatology·Kaushal K PrasadKartar Singh
Jan 1, 2014·World Journal of Gastroenterology : WJG·Gianluca IaniroGiovanni Cammarota
Jan 8, 2014·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Roberta CarusoGiovanni Monteleone
Oct 1, 2014·Nature Reviews. Gastroenterology & Hepatology·Steffen Husby, Joseph A Murray
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Emilio BrocchiRoberto Corinaldesi
Nov 4, 2008·Journal of Pediatric Gastroenterology and Nutrition·Margherita BonamicoUNKNOWN Società Italiana di Gastroenterologica, Epatologia, e Nutrizione Pediatrica
Oct 2, 2008·Journal of Clinical Gastroenterology·Kaushal Kishor PrasadKartar Singh
Sep 22, 2011·Journal of Clinical Gastroenterology·Raffaella NennaFabio Massimo Magliocca
Feb 24, 2015·Scandinavian Journal of Gastroenterology·Wolfgang EignerHarald Vogelsang
Dec 5, 2015·Scandinavian Journal of Gastroenterology·Caroline MonténDaniel Agardh
Jul 23, 2013·Gastrointestinal Endoscopy·Ravi N SharafBrooks D Cash
Mar 16, 2012·Pathology, Research and Practice·Alberto Ravelli, Vincenzo Villanacci
Oct 5, 2010·Gastrointestinal Endoscopy·Susana GonzalezPeter H R Green
Jul 16, 2010·Gastrointestinal Endoscopy·Benedetto MangiavillanoPier Alberto Testoni
Mar 31, 2009·Gastrointestinal Endoscopy·Vincenzo Villanacci
Feb 3, 2009·Gastrointestinal Endoscopy·Benedetto MangiavillanoEnzo Masci
Jun 3, 2008·Gastrointestinal Endoscopy·Peter H R Green
Feb 3, 2016·Gastroenterology·Peter D MooneyDavid S Sanders
Feb 28, 2004·Histopathology·N S Goldstein
Oct 19, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Samantha A StovenJoseph A Murray
Aug 31, 2006·Seminars in Diagnostic Pathology·Marie E Robert
May 20, 2015·Computers in Biology and Medicine·Gianluca IaniroGiovanni Cammarota
Jan 6, 2006·Alimentary Pharmacology & Therapeutics·G CammarotaG Gasbarrini
Jul 28, 2013·Gastrointestinal Endoscopy·Francesco ValituttiSalvatore Cucchiara
Aug 3, 2016·The American Journal of Gastroenterology·Matthew KurienDavid S Sanders
Sep 4, 2016·Gastroenterology·Georg Oberhuber, Harald Vogelsang
Dec 22, 2016·Expert Review of Gastroenterology & Hepatology·Luca ElliGovind K Makharia
Jan 19, 2005·The American Journal of Gastroenterology·Alberto RavelliVincenzo Villanacci
Oct 8, 2009·The American Journal of Gastroenterology·Dascha C WeirAlan M Leichtner
Feb 13, 2018·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Bhanwar Singh DhandhuSandeep Nijhawan
May 25, 2011·The American Journal of Gastroenterology·Kate E EvansDavid S Sanders
Jul 16, 2010·Journal of Clinical Gastroenterology·Rachel Levinson-CastielRaanan Shamir
May 19, 2010·Expert Review of Clinical Immunology·William Dickey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.