Mar 29, 2020

Diagnostic efficacy of contrast-enhanced ultrasound for breast lesions of different sizes: a comparative study with magnetic resonance imaging

The British Journal of Radiology
Chunxiao LiRong Wu


This study aimed to compare the diagnostic performance of contrast-enhanced ultrasound (CEUS), magnetic resonance imaging (MRI), and the combined use of the two modalities for differentiating breast lesions of different sizes. A total of 406 patients with 406 solid breast masses detected by conventional ultrasound (US) underwent both CEUS and MRI scans. Histological results were used as reference standards. The lesions were categorized into three groups according to size (Group 1, ≤ 20 mm; Group 2, > 20 mm, Group 3: total lesions). Sensitivity, specificity, accuracy, and receiver operating characteristic (ROC) curve analysis were used to assess the diagnostic performance of these imaging methods for breast lesions. There were 194 benign and 212 malignant breast lesions according to the histological diagnosis. Compared with MRI, CEUS demonstrated similar sensitivity in detecting breast cancer (p = 1.0000 for all) in all the three groups. With regard to specificity, accuracy, and the area under the ROC curve (Az) values, MRI showed a better performance than that shown by CEUS (p <0.05 for all), and the combination of the two modalities improved the diagnostic performance of CEUS alone significantly (p <0.05 for all) in all the th...Continue Reading

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Mentioned in this Paper

Comparative Study Research
Malignant Neoplasm of Breast
Diagnostic Imaging
Histology Procedure
Lesion of Breast
Magnetic Resonance Imaging

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