Diagnostic investigation of porcine periweaning failure-to-thrive syndrome: lack of compelling evidence linking to common porcine pathogens

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Yanyun HuangJohn Harding

Abstract

Porcine periweaning failure-to-thrive syndrome (PFTS), an increasingly recognized syndrome in the swine industry of North America, is characterized by the anorexia of nursery pigs noticeable within 1 week of weaning, and progressive loss of body condition and lethargy during the next 1-2 weeks. Morbidity caused by PFTS is moderate, but case fatality is high. The etiology of PFTS is presently unknown and may include infectious agent(s), noninfectious factors, or both. PFTS was identified in a high health status farm with good management in early 2007. A diagnostic investigation was undertaken to identify the pathological lesions of, and infectious agents associated with, pigs demonstrating typical clinical signs. Affected (PFTS-SICK) and unaffected (PFTS-HLTHY) pigs from an affected farm, and unaffected pigs from 2 unaffected farms, were examined. The most prevalent lesions in PFTS-SICK pigs were superficial lymphocytic fundic gastritis, atrophic enteritis, superficial colitis, lymphocytic and neutrophilic rhinitis, mild nonsuppurative meningoencephalitis, and thymic atrophy. Rotavirus A and Betacoronavirus 1 (Porcine hemagglutinating encephalomyelitis virus) were identified only in PFTS-SICK pigs, but the significance of the vi...Continue Reading

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Citations

Jul 6, 2014·Molecular Therapy : the Journal of the American Society of Gene Therapy·Rose A WhelanSusanne Hartmann
Nov 28, 2013·Influenza and Other Respiratory Viruses·Susan E DetmerJohn C Harding
Jul 22, 2018·The Veterinary Record·Joaquim Segalés
Apr 27, 2018·The Veterinary Record·Francesca BertoliniMax F Rothschild
Nov 11, 2018·The Veterinary Record·Giovanni FranzoJoaquim Segalés
Apr 23, 2019·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Francisco J Pallarés, Serafín Gómez
May 17, 2012·The Veterinary Record·J SegalésA Finestra

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Methods Mentioned

BETA
PCR

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