Diagnostic investigations in MS: which is the most sensitive?

Acta Neurologica Scandinavica
P SolaE Merelli

Abstract

In an attempt to establish the efficacy of the different diagnostic tests, 41 multiple sclerosis (MS) patients at different stages of the disease were studied by means of visual evoked potential (VEP) recording, T-lymphocyte subset determination cerebrospinal fluid (CSF) analysis and magnetic resonance (MR) imaging. MR and CSF oligoclonal bands (OB) were the most sensitive techniques for the diagnosis of MS, being positive in 88% of patients, while VEP and helper/suppressor (H/S) T-cell ratio were altered in 54% and 46% of patients respectively. Low significant agreement coefficient were found among the 4 tests and the major value, even though "fairly" significant, was between MR and OB.

References

Feb 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·L S HonigA Sazant
Feb 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·W I McDonald
Apr 1, 1988·Journal of the Neurological Sciences·J PaloJ Wikström
Jan 1, 1986·Neuroradiology·G ScottiC L Cazzullo
Feb 1, 1985·AJR. American Journal of Roentgenology·K R MaravillaR L Nunnally
Nov 1, 1985·AJR. American Journal of Roentgenology·J J SheldonM Viamonte
Apr 1, 1984·Journal of Neuroimmunology·H L WeinerS L Hauser
May 1, 1983·AJR. American Journal of Roentgenology·M Brant-ZawadzkiL Kaufman
Sep 1, 1983·Archives of Neurology·J J Gilbert, M Sadler
Mar 1, 1983·Annals of Neurology·C M PoserW W Tourtellotte
Jun 1, 1983·Annals of Neurology·S A LukesD Norman

❮ Previous
Next ❯

Citations

Jun 23, 1990·Lancet·J P ZanettaG Vincendon
Oct 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·P J TienariJ Palo
Feb 1, 1991·Ophthalmology·J I LimJ A Goodwin
Feb 1, 1995·Neurologic Clinics·H L WeinerD A Hafler

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.