Diagnostic Performance of Adaptive 4D Volume Perfusion CT for Detecting Metastatic Cervical Lymph Nodes in Head and Neck Squamous Cell Carcinoma

AJR. American Journal of Roentgenology
Munetaka MatobaHisao Tonami

Abstract

The purpose of this study was to investigate the diagnostic performance of adaptive 4D volume perfusion CT covering the entire neck for detecting metastatic nodes in patients with head and neck squamous cell carcinoma. Thirty patients with histologically confirmed disease were enrolled. The relation between perfusion parameters and nodal size was analyzed, and perfusion parameters were compared between metastatic and benign nodes. The diagnostic capability for detecting metastatic nodes was evaluated. Significant inverse correlations with nodal size were found for blood flow (r = -0.40, p = 0.002), blood volume (r = -0.32, p = 0.02), and permeability surface product (r = -0.27, p = 0.04) of the metastatic nodes. All three parameters had significantly higher values in association with nodal maximum diameter < 10 mm compared with diameter ≥ 10 mm (blood flow, p = 0.004; blood volume, p = 0.01; permeability surface product, p = 0.02). Among the nodes with maximum diameter < 10 mm, blood flow of the metastatic nodes was significantly higher than that of the benign nodes (p = 0.02), whereas among the nodes ≥ 10 mm in diameter, the mean transit time of the metastatic nodes was significantly lower than that of the benign nodes (p = 0....Continue Reading

References

Jun 26, 2001·Histopathology·K N NareshA M Borges
Oct 1, 2004·The British Journal of Radiology·K A Miles
Jul 13, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A A DünneJ A Werner
Feb 27, 2007·International Journal of Radiation Oncology, Biology, Physics·Ryuji MurakamiYasuyuki Yamashita
Feb 7, 2009·Radiologic Clinics of North America·Avinash R Kambadakone, Dushyant V Sahani
Feb 18, 2010·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·G PetraliaM Bellomi
Jul 29, 2011·European Journal of Radiology·Alexander W SauterMarius S Horger
Mar 1, 2012·European Radiology·K A MilesUNKNOWN Experimental Cancer Medicine Centre Imaging Network Group
Dec 21, 2012·AJR. American Journal of Roentgenology·Roberto García-FigueirasAntonio Gómez-Caamaño
Jul 6, 2013·AJNR. American Journal of Neuroradiology·S Y JoS K Mukherji
Jan 7, 2014·European Journal of Radiology·Ahmed Abdel Khalek Abdel RazekNermin Yehia Soliman

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Citations

Apr 15, 2021·European Journal of Radiology Open·Shubham SuryavanshiNita Khurana
May 1, 2021·Diagnostics·Rima HajjoAlexander Tropsha
May 17, 2021·La Radiologia medica·Reza AssadsangabiSeyed Ali Nabavizadeh

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