Diagnostic Performance of an Advanced Modeled Iterative Reconstruction Algorithm for Low-Contrast Detectability with a Third-Generation Dual-Source Multidetector CT Scanner: Potential for Radiation Dose Reduction in a Multireader Study

Radiology
Justin SolomonEhsan Samei

Abstract

To assess the effect of radiation dose reduction on low-contrast detectability by using an advanced modeled iterative reconstruction (ADMIRE; Siemens Healthcare, Forchheim, Germany) algorithm in a contrast-detail phantom with a third-generation dual-source multidetector computed tomography (CT) scanner. A proprietary phantom with a range of low-contrast cylindrical objects, representing five contrast levels (range, 5-20 HU) and three sizes (range, 2-6 mm) was fabricated with a three-dimensional printer and imaged with a third-generation dual-source CT scanner at various radiation dose index levels (range, 0.74-5.8 mGy). Image data sets were reconstructed by using different section thicknesses (range, 0.6-5.0 mm) and reconstruction algorithms (filtered back projection [FBP] and ADMIRE with a strength range of three to five). Eleven independent readers blinded to technique and reconstruction method assessed all data sets in two reading sessions by measuring detection accuracy with a two-alternative forced choice approach (first session) and by scoring the total number of visible object groups (second session). Dose reduction potentials based on both reading sessions were estimated. Results between FBP and ADMIRE were compared by ...Continue Reading

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Citations

Oct 29, 2015·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Joseph MadamesilaRao Khan
Jan 26, 2017·Medical Physics·Yakun ZhangEhsan Samei
Apr 13, 2017·AJR. American Journal of Roentgenology·Alice E HuangCynthia H McCollough
Mar 24, 2018·AJR. American Journal of Roentgenology·Hub BoereCecile R L P N Jeukens
Jan 13, 2018·European Radiology·Saravanabavaan SuntharalingamKai Nassenstein
Aug 18, 2018·Journal of Applied Clinical Medical Physics·Lianna D Di MasoJessica R Miller
Nov 13, 2018·Medical Physics·P KhobragadeTaly Gilat Schmidt
Nov 16, 2019·Journal of Applied Clinical Medical Physics·Jun-Bong ShinTae Suk Suh
Apr 14, 2019·Medical Physics·Baiyu ChenRicardo Otazo
Jul 29, 2020·Journal of Applied Clinical Medical Physics·Juliane ConzelmannPaul Jahnke
Mar 27, 2020·Investigative Radiology·Hatem Alkadhi, André Euler

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