Diagnostic performance of an expert system for interpretation of 99mTc MAG3 scans in suspected renal obstruction

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Andrew TaylorEva Dubovsky

Abstract

The purpose of the study was to compare diuresis renography scan interpretation generated by a renal expert system with the consensus interpretation of 3 expert readers. The expert system was evaluated in 95 randomly selected furosemide-augmented patient studies (185 kidneys) obtained for suspected obstruction; there were 55 males and 40 females with a mean age +/- SD of 58.6 +/- 16.5 y. Each subject had a baseline (99m)Tc-mercaptoacetyltriglycine ((99m)Tc-MAG3) scan followed by furosemide administration and a separate 20-min acquisition. Quantitative parameters were automatically extracted from baseline and furosemide acquisitions and forwarded to the expert system for analysis. Three experts, unaware of clinical information, independently graded each kidney as obstructed/probably obstructed, equivocal, and probably nonobstructed/nonobstructed; experts resolved differences by a consensus reading. These 3 expert categories were compared with the obstructed, equivocal, and nonobstructed interpretations provided by the expert system. Agreement was assessed using weighted kappa, and the predictive accuracy of the expert system compared with expert readers was assessed by the area under receiver-operating-characteristic (ROC curve)...Continue Reading

References

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May 31, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Ernest V GarciaEva Dubovsky

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Citations

May 31, 2012·European Journal of Nuclear Medicine and Molecular Imaging·Ernest V GarciaEva Dubovsky
Sep 1, 2009·Brain Imaging and Behavior·Michelle T Fodero-TavolettiVictor L Villemagne
Nov 23, 2006·AJR. American Journal of Roentgenology·Fabio P EstevesErnest V Garcia
May 14, 2011·Journal of Nuclear Medicine Technology·Russell D FolksAndrew T Taylor
Nov 29, 2011·Seminars in Nuclear Medicine·Andrew T TaylorAlain Prigent
Nov 30, 2010·Seminars in Nuclear Medicine·Martin Sámal
Jun 2, 2011·BMC Medical Research Methodology·Qingjiang HouMatthew S Mayo
May 25, 2016·Molecular & Cellular Proteomics : MCP·John W FroehlichRichard S Lee
Mar 5, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Andrew T Taylor
Jan 1, 2020·Journal of the American Statistical Association·Changgee ChangQi Long

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