Diagnostic performance of combined noninvasive anatomic and functional assessment with dual-source CT and adenosine-induced stress dual-energy CT for detection of significant coronary stenosis

AJR. American Journal of Roentgenology
Sung Min KoHyun Keun Chee

Abstract

The purpose of our study was to prospectively evaluate the incremental diagnostic value of combined dual-source coronary CT angiography (CTA) and CT myocardial perfusion imaging (MPI) for the detection of significant coronary stenoses. Forty-five patients with known coronary artery disease detected by dual-source coronary CTA were investigated by adenosine-induced stress dual-source CTA and conventional coronary angiography. Analysis was performed in three steps: classification of coronary stenosis severity using dual-source coronary CTA, identification of myocardial perfusion defects using rest and stress CT MPI, and reclassification of coronary stenosis severity according to combined dual-source coronary CTA and CT MPI. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of dual-source coronary CTA before and after CT MPI were calculated on a per-vessel basis compared with conventional coronary angiography as the standard of reference. Dual-source coronary CTA revealed 87 significantly stenotic vessels in 45 patients. Conventional coronary angiography revealed significant stenoses in 73 vessels in 42 patients. CT MPI showed myocardial perfusion defects in 81 vessel territories in...Continue Reading

References

Feb 20, 2003·Circulation·Richard L MorinCynthia H McCollough
Apr 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Akira KurataJitsuo Higaki
Jul 4, 2006·Journal of the American College of Cardiology·Richard T GeorgeAlbert C Lardo
May 4, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Oliver GaemperliPhilipp A Kaufmann
Oct 2, 2007·Journal of the American College of Cardiology·Kiran R NandalurRuth C Carlos
Nov 17, 2007·Investigative Radiology·Richard T GeorgeAlbert C Lardo
Nov 15, 2008·European Journal of Radiology·Florian SchwarzPeter L Zwerner
Jan 22, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Cesar A SantanaPaolo Raggi
Sep 12, 2009·Journal of the American College of Cardiology·Ron BlanksteinRicardo C Cury
Nov 26, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·David R OkadaRicardo C Cury

❮ Previous
Next ❯

Citations

Aug 22, 2013·Journal of Cardiovascular Translational Research·Amit R PatelVictor Mor-Avi
Mar 13, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Alexander Becker, Christoph Becker
Dec 21, 2013·Radiology·Alexia RossiGabriel P Krestin
Sep 12, 2013·Future Cardiology·Yasmin S Hamirani, Christopher M Kramer
Apr 4, 2014·The International Journal of Cardiovascular Imaging·Sung Min KoMeong Gun Song
Jul 25, 2012·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M F L MeijsP A Doevendans
Aug 20, 2014·The British Journal of Radiology·A M BucherB Ruzsics
Nov 10, 2015·Expert Review of Cardiovascular Therapy·Ibrahim DanadJames K Min
Jan 18, 2016·Revista Española De Cardiología·Sara SeitunCarlo Ferro
Apr 30, 2014·Revista Española De Cardiología·Carlos DelgadoMarcelo Sanmartin
Nov 14, 2015·JACC. Cardiovascular Imaging·Pedro de Araújo GonçalvesHector M Garcia-Garcia
Feb 29, 2016·Current Cardiology Reports·Martin J WilleminkPál Maurovich-Horvat
Feb 15, 2015·Academic Radiology·Patricia M CarrascosaGaston A Rodriguez-Granillo
Mar 18, 2015·European Journal of Radiology·Paola M CannaòCarlo N De Cecco
May 21, 2014·Clinical Physiology and Functional Imaging·Jakob De GeerJan Engvall
Mar 5, 2016·Clinical Radiology·A M den HarderT Leiner
Mar 27, 2015·The International Journal of Cardiovascular Imaging·Sung Min KoIhn Ho Cho
Jun 13, 2015·JACC. Cardiovascular Imaging·Ibrahim DanadJames K Min
Mar 3, 2015·Radiologic Clinics of North America·Thomas G FlohrFelix G Meinel
Mar 3, 2015·Radiologic Clinics of North America·Carlo Nicola De CeccoU Joseph Schoepf
Feb 26, 2015·AJR. American Journal of Roentgenology·Akos Varga-SzemesU Joseph Schoepf
Feb 17, 2015·BioMed Research International·Lei XuZhanming Fan
Dec 30, 2014·AJR. American Journal of Roentgenology·Frank J RybickiMelvin E Clouse
Jul 19, 2016·European Journal of Radiology·Kwang Nam JinU Joseph Schoepf
Oct 27, 2016·Current Treatment Options in Cardiovascular Medicine·Gianluca PontoneMauro Pepi
Nov 1, 2012·AJR. American Journal of Roentgenology·Rozemarijn VliegenthartU Joseph Schoepf
Sep 15, 2016·Heart·Harjit ChahalMario J Garcia
Mar 16, 2017·Journal of Computer Assisted Tomography·Patricia CarrascosaGaston A Rodriguez-Granillo
Nov 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kevin KaliszPrabhakar Rajiah
Jan 28, 2014·Genomics & Informatics·Hyun Keun Chee, S June Oh
Mar 28, 2020·Medical Physics·Cynthia H McColloughNorbert J Pelc
Nov 9, 2018·BioMed Research International·Sara SeitunGian Paolo Bezante
Jul 1, 2016·Current Cardiovascular Imaging Reports·Amita SinghAmit R Patel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.