Diagnostic performance of dual-energy CT for the detection of traumatic bone marrow lesions in the ankle: comparison with MR imaging

Radiology
Roman GuggenbergerHatem Alkadhi

Abstract

To evaluate prospectively the performance of noncalcium images reconstructed from dual-energy (DE) computed tomography (CT) for the diagnosis of bone marrow lesions in patients with acute ankle joint trauma in comparison with magnetic resonance (MR) images. The study had local ethics board approval, and written informed consent was obtained. Thirty consecutive patients (15 women; mean age, 34 years±11.8 [standard deviation]) underwent dual-source DE CT (80 kVp and 140 kVp with tin filter) and MR imaging within 1 day following acute ankle trauma. DE CT data were postprocessed by using a three-material decomposition algorithm for generating noncalcium images. MR and noncalcium images were graded by two blinded, independent readers using a four-point system (1=distinct bone marrow lesion, 4=no lesion); CT numbers in noncalcium images were calculated by a third reader. MR imaging interpretations served as the reference standard. Interreader agreement for qualitative grading of DE CT images was substantial (κ=0.66). The respective sensitivity, specificity, positive predictive value, and negative predictive value of DE CT for depicting distinct bone marrow lesions for both readers were 90.0% each, 80.5% and 81.6%, 25.4% and 26.5%, an...Continue Reading

References

Sep 1, 1988·Radiology·J B Vogler, W A Murphy
Jun 1, 1988·Radiology·L Yao, J K Lee
Aug 14, 1998·Acta Orthopaedica Scandinavica·C RanggerA Kreczy
Dec 5, 2000·The Journal of the American Academy of Orthopaedic Surgeons·B P Boden, D C Osbahr
Jan 5, 2002·Radiology·Marco ZanettiJuerg Hodler
Mar 1, 2002·European Radiology·Dominik Weishaupt, Mark E Schweitzer
Jan 4, 2003·Radiology·Patrick M BossuytUNKNOWN Standards for Reporting of Diagnostic Accuracy
Mar 18, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Robert H ChoplinJoshua M Farber
Aug 31, 2004·AJR. American Journal of Roentgenology·Ville V HaapamakiSeppo K Koskinen
Feb 3, 2006·Radiology·Simone S BoksSita M A Bierma-Zeinstra
Nov 14, 2006·The American Journal of Sports Medicine·Maria H NivaHarri K Pihlajamaki
Dec 8, 2006·European Radiology·Thorsten R C JohnsonChristoph R Becker
Jul 10, 2007·European Radiology·Veronika ZublerMarco Zanetti
Dec 21, 2007·AJR. American Journal of Roentgenology·Donna G BlankenbakerStephanie A Koplin
Mar 14, 2008·European Journal of Radiology·W A ThiryayiA J Freemont
Jun 7, 2008·European Journal of Radiology·V Mandalia, J H L Henson
Dec 19, 2008·Radiology·Tal Laor, Diego Jaramillo
Jun 23, 2009·AJR. American Journal of Roentgenology·Benjamin M YehSven Prevrhal
Dec 10, 2009·Investigative Radiology·Paul StolzmannHatem Alkadhi
Jan 26, 2011·Investigative Radiology·Michael A FischerRobert Goetti
Feb 19, 2011·Seminars in Musculoskeletal Radiology·James TehJulia Newton

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Citations

Jun 28, 2013·World Journal of Radiology·Jan HansmannUlrike I Attenberger
Nov 6, 2015·The British Journal of Radiology·Leyla KaracaU Gulsum Bayrakturan
Mar 5, 2013·Seminars in Roentgenology·Trenton D RothRobert H Choplin
May 2, 2014·Diagnostic and Interventional Imaging·M OhanaC Roy
Jun 6, 2015·Radiologic Clinics of North America·Patrick D McLaughlinSavvas Nicolaou
Feb 26, 2015·AJR. American Journal of Roentgenology·Christoph ThomasMarius Horger
Nov 5, 2016·Academic Radiology·Domin NaYeonggul Jang
Aug 16, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·M BiondiL Volterrani
Nov 22, 2016·Radiology·Paul I MallinsonHugue A Ouellette
Mar 13, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jeremy R WortmanAaron D Sodickson
Feb 23, 2018·AJR. American Journal of Roentgenology·Ismail T AliSavvas Nicolaou
Sep 5, 2018·Radiology·Martin J WilleminkDominik Fleischmann
Oct 30, 2018·Journal of Computer Assisted Tomography·Jeffrey R SachsMichael E Zapadka
May 1, 2019·AJR. American Journal of Roentgenology·Prabhakar RajiahNaveen Subhas
Mar 27, 2020·Investigative Radiology·Hatem Alkadhi, André Euler
Aug 22, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Prabhakar RajiahShuai Leng
Feb 15, 2020·European Radiology·Min ChenLennart Jans
May 7, 2020·Radiology Research and Practice·Ramin Ghasemi ShayanMona Fazel Ghaziyani
Jul 5, 2017·European Radiology·Takeshi FukudaKunihiko Fukuda
Nov 20, 2019·The Indian Journal of Radiology & Imaging·Parang S Sanghavi, Bhavin G Jankharia

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