Diagnostic performance of endocytoscopy for evaluating the invasion depth of different morphological types of colorectal tumors

Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society
Toyoki KudoHaruhiro Inoue

Abstract

Endocytoscopy (EC) is a next-generation endoscopic technique that enables diagnostic imaging at 450× magnification. In the present study, we retrospectively evaluated the diagnostic performance of EC and magnifying chromoendoscopy (MCE) for diagnosing the invasion depth of colorectal tumors. We investigated 330 lesions with a ≥10-mm tumor diameter that could be diagnosed by both MCE and EC. The lesions were classified according to morphological type as follows: laterally spreading type-granular (LST-G), laterally spreading type-non-granular (LST-NG), protruding, or depressed. After all lesions had been classified by both pit pattern and EC, qualitative and quantitative (invasion depth) diagnoses were made. The diagnostic accuracy was then compared between pit pattern classification and EC classification. Diagnostic accuracy of EC classification was significantly higher for LST-NG lesions (90.5%) than for protruding lesions (80.6%) (P < 0.05). Diagnostic accuracy for LST-NG lesions was significantly higher with EC classification (90.5%) than with pit pattern classification (79.3%) (P < 0.001). Comparison of the diagnostic performance of EC3a findings using EC classification between LST-NG and protruding lesions revealed a sensit...Continue Reading

References

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Aug 29, 2013·Journal of Gastroenterology and Hepatology·Shin-ei KudoShigeharu Hamatani
Sep 11, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Katsuro IchimasaHaruhiro Inoue
Oct 15, 2013·Gastrointestinal Endoscopy·Makoto KutsukawaShigeharu Hamatani

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Citations

Nov 24, 2016·Gastrointestinal Endoscopy·Toyoki KudoHaruhiro Inoue
Nov 28, 2020·United European Gastroenterology Journal·Roel M M BogieAd A M Masclee
Feb 20, 2021·Cancer Management and Research·Da-Huan LiLiang-Bi Xu
Jun 27, 2021·Best Practice & Research. Clinical Gastroenterology·Ishita BaruaMichael Bretthauer
Jul 8, 2021·Clinical Endoscopy·Masashi MisawaHaruhiro Inoue
Feb 29, 2020·Visceral Medicine·Timo RathMarkus F Neurath

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