Diagnostic performance of hybrid cardiac SPECT/CT imaging for patients with takotsubo cardiomyopathy

European Journal of Hybrid Imaging
Yasuro SugiharaWataru Shimizu

Abstract

The diagnostic performance of SPECT-only imaging for takotsubo cardiomyopathy (TC) is limited due to the lack of coronary artery distribution information. The aim of this study was to evaluate the diagnostic performance of hybrid cardiac SPECT/CT for patients with TC or acute coronary syndrome (ACS). Twenty-two patients with apical ballooning left ventricular (LV) dysfunction who underwent cardiac perfusion SPECT using 99mTc-methoxy-isobutyl-isonitrile (MIBI), cardiac fatty-acid metabolism SPECT using 123I-beta-methyl-P-iodophenyl-pentadecanoic acid (BMIPP), cardiac CT, and hybrid cardiac SPECT/CT imaging were analyzed. On the SPECT images, MIBI and BMIPP defects were quantified using a 17-segment model with a 5-point grading system and a summed MIBI defect score (SMDS), summed BMIPP defect score (SBDS), and summed mismatch score (SMS) were calculated. Furthermore, apical and non-apical MDS, BDS, and mismatch scores (A- and NA-MDS, A- and NA-BDS, and A- and NA-MS) were calculated. These quantitative scores were compared between the TC (n = 11) and ACS (n = 11) groups, and the diagnostic performances of SPECT-only imaging and hybrid SPECT/CT imaging were compared. For all patients, the diagnoses of both SPECT-only and SPECT/CT i...Continue Reading

References

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Citations

Apr 23, 2020·Journal of Neurology·A BersanoH S Markus
Jul 6, 2020·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Tim Van den WyngaertOra Israel

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Methods Mentioned

BETA
imaging technique

Software Mentioned

StatMate IV
CardIQ Fusion

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