Diagnostic Performance of LI-RADS Treatment Response Algorithm for Hepatocellular Carcinoma: Adding Ancillary Features to MRI Compared with Enhancement Patterns at CT and MRI

Radiology
Sungeun ParkJeong Min Lee

Abstract

Background The Liver Imaging Reporting and Data System Treatment Response (LR-TR) algorithm is used to assess the response of hepatocellular carcinoma (HCC) to local-regional therapy (LRT) based on enhancement patterns. The potential value of adding MRI ancillary features (AFs) needs to be investigated. Purpose To evaluate the potential application of MRI AFs in category adjustment to detect pathologic tumor viability in comparison with the LR-TR algorithm in CT and gadoxetic acid-enhanced MRI. Materials and Methods This retrospective study included patients with HCCs treated with LRT followed by surgical resection or liver transplantation between January 2014 and December 2017 who underwent both post-LRT CT and gadoxetic acid-enhanced MRI. For each treated observation, treatment response (TR) categories were assigned based on a consensus reading of three radiologists according to the LR-TR algorithm in CT and MRI and according to the MRI-modified TR algorithm in which MRI AFs were allowed for category adjustment. The diagnostic performances of CT LR-TR viable, MRI LR-TR viable, and MRI-modified TR viable categories were compared intraindividually with the McNemar test, with pathologic tumor viability used as a reference standa...Continue Reading

References

Feb 23, 2010·Seminars in Liver Disease·Riccardo Lencioni, Josep M Llovet
Apr 14, 2010·Journal of Hepatology·Christian TosoPietro Majno
Mar 5, 2013·Archives of Pathology & Laboratory Medicine·Joshua Anspach HansonKisha Anne Mitchell
Jun 26, 2013·AJR. American Journal of Roentgenology·Vahid YaghmaiBachir Taouli
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Nov 14, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Khaled M ElsayesClaude B Sirlin
Oct 6, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Milena CernyAn Tang
May 1, 2019·Radiology·Erin L ShropshireMustafa R Bashir
Jun 7, 2019·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Keungmo YangSeung K Yoon

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Citations

Mar 4, 2021·Radiology·Mustafa R Bashir, Mishal Mendiratta-Lala
Jun 10, 2021·Journal of Hepatocellular Carcinoma·Guilherme Moura CunhaClaude B Sirlin
Jun 10, 2021·Abdominal Radiology·Roopa RamMishal Mendiratta-Lala

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