PMID: 29847063Mar 1, 2017Paper

Diagnostic problems of the mucormycosis of the maxillary sinus Case presentation

Fogorvosi szemle
Kinga BerczyGyula Prinz

Abstract

Mucormycosis is a fulminant opportunistic infection with significant mortality in susceptible individuals. Although mortality rates vary widely (30 to 100%) according to professional literature, recently in instances with no central nervous system (CNS) involvement the survival rate averages varies between 50 and 80% owing to complex therapy. With CNS involvement, however, the fatality rate is over 80%. Predisposing diseases include diabetes mellitus, malnutrition, hematologi- cal diseases, neutropenia, burns, surgical procedures, antibiotic treatments, long-term steroid therapy and immunosuppressive therapy. Mucormycosis may at times arise even in -immunocompetent individuals. It has diverse clinical forms with the most frequent forms being rhino-maxillary and rhino-oculocerebral (the latter of which is characterized by a high mortality rate). They mainly enter the body through inhalation, with saprophytic mucor species often demonstrable in the upper respiratory tracts, which are nevertheless non-pathogenic in most healthy individuals. The spores may also enter percutaneously through traumas, skin lesions, insect bites, or injections (e.g. through intravenous drug use); as well as via the alimentary tract with contaminated fo...Continue Reading

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