PMID: 7543604Sep 1, 1995Paper

Diagnostic significance of prostate specific antigen and the development of a mass screening system for prostate cancer

The Journal of Urology
K ImaiJ Sato

Abstract

The significance of prostate specific antigen (PSA) in the mass screening for prostate cancer was investigated. A total of 4,375 PSA, digital rectal and transrectal ultrasonographic examinations was performed on 3,526 subjects. Among the 3 modalities, PSA had the highest sensitivity (80.4%) and positive predictive value (45.1%). We established age-specific reference PSA ranges for normal Japanese men, and demonstrated the significance of PSA density and PSA velocity. The significance of PSA as a prostate cancer screening modality should be evaluated across multiple age ranges and in combination with previous PSA data and/or prostate volume.

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Citations

Apr 27, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·K MatsumotoT Samori
May 16, 2000·International Journal of Urology : Official Journal of the Japanese Urological Association·Y KubotaH Yamanaka
Dec 23, 1998·Japanese Journal of Clinical Oncology·S EgawaK Koshiba
Apr 7, 2009·Japanese Journal of Clinical Oncology·Chisato HamashimaTomotaka Sobue
Dec 9, 1997·Journal of the National Cancer Institute·A ShibataR S Paffenbarger
Jun 2, 1998·The Tohoku Journal of Experimental Medicine·N OhtakeK Tari
Apr 1, 1997·The Journal of Urology·D N Osegbe
May 1, 1997·The Urologic Clinics of North America·M C Beduschi, J E Oesterling
Jul 2, 1998·The Journal of Urology·J G BorerR J Macchia
Jan 12, 2005·The Journal of Urology·Amit GuptaClaus G Roehrborn
Aug 14, 1998·Japanese Journal of Cancer Research : Gann·N YoshimuraO Yoshida
May 15, 2007·Urologia Internationalis·Minoru HorinagaTsuneharu Miki

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