PMID: 7540773Mar 1, 1995Paper

Diagnostic significance of serum neuron-specific enolase and myelin basic protein assay in patients with acute head injury

Surgical Neurology
Y YamazakiT Ohwada

Abstract

Neuron-specific enolase (NSE) and myelin basic protein (MBP) in the peripheral venous blood (PVB) have been reported to be sensitive markers for judging the prognosis of patients with head injury. However, to our knowledge, the levels of NSE and MBP in the internal jugular venous blood (IJVB) have never been studied. In 25 patients with acute head injury, blood samples were taken from the internal jugular vein and the peripheral vein at the same time before any medical or surgical procedure was performed. The levels of NSE and MBP in the both venous blood samples were measured. The time interval between injury and sampling was 1.5-8.0 hours (mean 4.3 hours). The levels of NSE and MBP in the IJVB were compared to those in the PVB. The relationship between the clinical outcome and the serum levels of those was evaluated. The levels of NSE and MBP in the IJVB were almost equal to those in the PVB. The levels of NSE and MBP were significantly higher in the patients who died than in those who survived. In the survivors, the levels of NSE and MBP in the IJVB were 17.6 +/- 11.4 ng/ml and 1.4 +/- 1.5 ng/ml, whereas in the patients who died, both levels were elevated to 51.3 +/- 27.3 ng/ml (p < 0.005) and to 11.3 +/- 9.5 ng/ml (p < 0.01...Continue Reading

References

Jan 1, 1978·Immunological Reviews·G A Hashim
Jan 16, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·J W PalfreymanJ G Ratcliffe
Jul 31, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·E KaiserW Worofka
Sep 1, 1985·Critical Care Medicine·T W NoseworthyT A McPherson
Jul 13, 1974·Lancet·G Teasdale, B Jennett
Jul 15, 1983·Clinica Chimica Acta; International Journal of Clinical Chemistry·R DauberschmidtJ Gross

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Citations

Jan 1, 1997·Acta neurochirurgica·C WoertgenA Brawanski
Jul 20, 2012·Current Neurology and Neuroscience Reports·Richa Sharma, Daniel T Laskowitz
May 25, 2007·Neurocritical Care·Stephen M BloomfieldJonathan Brisman
Apr 25, 2012·Neurocritical Care·Sabrina GiacoppoSilvia Marino
Jun 1, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·V SelakovicL Radenovic
Jun 12, 2004·The Journal of Pediatrics·Kent P Hymel
Mar 25, 2011·Journal of Neurotrauma·Andrea GyorgyDenes V Agoston
Dec 21, 2012·Journal of Neurotrauma·Douglas H SmithJohn T Povlishock
Apr 17, 2002·The Journal of Trauma·Tor Ingebrigtsen, Bertil Romner
Sep 23, 2003·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Britt-Marie StålnackePeter Sojka
Oct 13, 2006·The Journal of Trauma·Demetrios DemetriadesLinda S Chan
Nov 20, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·J R De KruijkA Twijnstra
Aug 2, 2006·Critical Care : the Official Journal of the Critical Care Forum·Nuala J Meyer, Jesse B Hall
Nov 23, 2006·Critical Care : the Official Journal of the Critical Care Forum·Eric B Milbrandt, Derek C Angus
Oct 19, 2011·Biomarkers in Medicine·Asla Pitkänen, Katarzyna Lukasiuk
Feb 28, 2002·Annals of Emergency Medicine·George J ShawFrank P Zemlan
Jul 17, 2014·Critical Care : the Official Journal of the Critical Care Forum·Ségolène MrozekThomas Geeraerts
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·K J BeckerJ M Hallenbeck
Apr 1, 2014·Clinical Proteomics·Sean ShenJoseph A Loo
Dec 1, 2011·Translational Stroke Research·Zhiqun ZhangKevin K W Wang
Apr 17, 2013·Current Translational Geriatrics and Experimental Gerontology Reports·Linda PapaCarolina F Braga
Jul 1, 2006·Brain Injury : [BI]·Jeffrey J BazarianTorgney Stigbrand
Jan 30, 2016·Medicina intensiva·E Gordillo-EscobarF Murillo-Cabezas
Jun 20, 2008·Parkinsonism & Related Disorders·Radu ConstantinescuLars Rosengren
May 15, 2007·The American Journal of Emergency Medicine·Cemil KavalciDilara Seckin
Jun 15, 2004·Brain Pathology·Jose A PinedaRonald L Hayes
Jan 27, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jeffrey J BazarianLynn Cimpello
Apr 14, 2010·The European Journal of Neuroscience·Ming C LiuKevin K W Wang
May 29, 2013·CNS Neuroscience & Therapeutics·Shoji YokoboriRoss Bullock
Aug 22, 2015·The Physician and Sportsmedicine·Tad SeifertJohnny Benjamin
Aug 16, 2005·Expert Review of Proteomics·Kevin K W WangRonald L Hayes
Jun 17, 2015·Current Pain and Headache Reports·Tad Seifert, Victoria Shipman
Apr 2, 2014·BioMed Research International·André Mendes ArentAlcir Luiz Dafre
Feb 1, 2012·Brain Research Bulletin·Enci Mary KanJia Lu

❮ Previous
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