Diagnostic utility and clinical significance of naso- and oropharyngeal samples used in a PCR assay to diagnose Mycoplasma pneumoniae infection in children with community-acquired pneumonia

Journal of Clinical Microbiology
Ian C MichelowR Doug Hardy

Abstract

PCR assays of naso- and oropharyngeal samples among hospitalized children appear equally effective for the diagnosis of serologically confirmed community-acquired mycoplasmal pneumonia. However, the combination of results from both sites yields optimal sensitivity (57%), specificity (98%), and positive (92%) and negative (82%) predictive values when compared with Mycoplasma pneumoniae enzyme-linked immunosorbent assay.

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Citations

Apr 16, 2009·Current Infectious Disease Reports·Ken B Waites, T Prescott Atkinson
Oct 31, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Monica Fonseca-AtenR Doug Hardy
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Aug 30, 2008·FEMS Microbiology Reviews·Thomas Prescott AtkinsonKen B Waites
Mar 1, 2012·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kensei GotohTakao Ozaki
Mar 22, 2014·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Wujun JiangZhengrong Chen
May 23, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Preeta K KuttyLauri A Hicks
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Jan 26, 2006·Journal of Medical Microbiology·David PitcherTimothy G Harrison
Jun 13, 2015·Health Technology Assessment : HTA·Helen McConachieKatrina Williams
Jul 1, 2010·Expert Review of Anti-infective Therapy·Frédéric Lamoth, Gilbert Greub
Aug 2, 2012·Paediatrics & Child Health·N Le Saux, Jl Robinson
May 28, 2014·Pediatrics·Eric BiondiAngela Dixon

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