PMID: 6988464Feb 1, 1980Paper

Diagnostic value and biological significance of antibody-coated bacteria in urine

Journal of Clinical Pathology
C MengoliL A Scuro

Abstract

The incidence of antibody-coated bacteria (ACB) in the urinary sediments as an indication of the site of urinary tract infections (UTI) was investigated in 103 adult subjects with persistent bacteriuria by means of a direct immunofluorescence technique.ACB were found in 49 of 58 (84.5%) subjects with long-standing upper urinary tract obstruction and in 5 of 45 (11.1%) with lower UTI; this difference was statistically significant (X(2) = 51.79; P<0.001). The group with upper UTI was further subdivided according to renal function (patients with renal insufficiency had both bilateral obstruction and bilateral renal damage); 21 positive results were obtained in 27 (77.8%) patients with normal renal function, whereas 28 positive cases were observed among 31 (90.3%) patients with chronic renal insufficiency. Thus the degree of renal involvement also seemed to influence the outcome of the test. Within the group of lower UTI, a higher rate of ;false-positive' results was obtained in 14 patients with symptomatic long-standing infection (21.4%) than in 31 subjects with asymptomatic bacteriuria (6.4%). The three major immunoglobulin classes and the secretory component were studied in 42 cases. Of these, 29 were found to be positive for AC...Continue Reading

References

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Citations

Oct 1, 1980·Journal of Clinical Pathology·A J Howie, D W Burdon
Nov 1, 1990·Journal of Clinical Pathology·A GallowayK R Krishnan
Dec 1, 1986·Bulletin of Environmental Contamination and Toxicology·R B HarveyT D Phillips
Jan 1, 1986·Bulletin of Environmental Contamination and Toxicology·R B HarveyN D Heidelbaugh
Mar 1, 1986·The British Journal of Nutrition·S J Fairweather-Tait, M J Minski
Mar 8, 2014·PLoS Pathogens·Melvyn W YapJonathan P Stoye
Nov 14, 2012·Journal of the American Animal Hospital Association·Nicole SmeeGreg Grauer

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