Diagnostic value of high-resolution CT in the evaluation of chronic infiltrative lung disease in children

AJR. American Journal of Roentgenology
Stephanie VrielynckJacques de Blic

Abstract

The purpose of this study was to evaluate the accuracy of CT in the diagnosis of chronic infiltrative lung disease in children. Fifty-nine patients selected over a 14-year period (29 girls, 30 boys; mean age, 6 +/- 4.9 years; range, 2 months-18 years) had nine disorders. CT scans were evaluated independently by two experienced chest radiologists, who were unaware of pathologic or clinical data. The radiologists recorded specific CT findings of infiltrative lung disease and were asked to give the most likely diagnosis and up to two differential diagnoses. Descriptive statistic analysis was followed by logistic regression analysis for each elementary lesion on the grid of abnormalities. A correct first-choice diagnosis was made in 38% of CT observations. The correct diagnosis was among the three main choices in 59% of CT observations. Pulmonary alveolar proteinosis (n = 18) was most frequently correctly diagnosed; it was the first-choice diagnosis 47% of the time and among the three main choices 72% of the time. The correct first-choice diagnosis of idiopathic pulmonary fibrosis (n = 16) was made 43% of the time; of hypersensitivity pneumonitis (n = 4), 37% of the time; of sarcoidosis (n = 7), 28% of the time; of idiopathic pulmo...Continue Reading

References

May 1, 1989·AJR. American Journal of Roentgenology·J E Takasugi, J D Godwin
Dec 1, 1988·Radiology·J D GodwinJ E Takasugi
Sep 1, 1993·Pediatric Pulmonology·L L Fan, C Langston
Oct 6, 1997·American Journal of Respiratory and Critical Care Medicine·L L Fan, C A Kozinetz
Sep 2, 1999·AJR. American Journal of Roentgenology·D A LynchL L Fan
Feb 5, 2000·AJR. American Journal of Roentgenology·S J CopleyD M Hansell
Sep 16, 2000·Clinical Radiology·D M Koh, D M Hansell
Oct 12, 2000·The European Respiratory Journal·A BarbatoM Zach
Oct 20, 2000·Medicine·L Le ClaincheJ De Blic
Apr 20, 2001·AJR. American Journal of Roentgenology·J M HolbertR M Rogers
Jul 21, 2001·American Journal of Respiratory and Critical Care Medicine·G W HunninghakeM Millard
Jun 5, 2002·American Journal of Respiratory and Critical Care Medicine·Leland L Fan, Claire Langston
Feb 20, 2003·AJR. American Journal of Roentgenology·Mitsuhiro KoyamaNestor L Müller
Jul 17, 2004·American Journal of Respiratory and Critical Care Medicine·Kevin R FlahertyFernando J Martinez
Sep 18, 2004·Pediatric Pulmonology·Leland L FanClaire Langston
Oct 2, 2004·The European Respiratory Journal·A Clement, UNKNOWN ERS Task Force
Nov 9, 2004·Paediatric Respiratory Reviews·Jacques de Blic
May 10, 2005·American Journal of Respiratory and Critical Care Medicine·Talmadge E King
Jun 21, 2005·Pediatric Pulmonology·Robin R DeterdingClaire Langston
Jul 1, 2005·Radiology·David A LynchTalmadge E King
Jul 1, 2006·American Journal of Respiratory and Critical Care Medicine·Ganesh RaghuGerry Oster
Sep 22, 2007·American Journal of Respiratory and Critical Care Medicine·Gail H DeutschUNKNOWN ChILD Research Co-operative
Feb 4, 2009·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kelby G Maher, Scot T Bateman

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Citations

May 1, 2010·Pediatric Radiology·K Haran Jogeesvaran, Catherine M Owens
Jun 26, 2012·Indian Pediatrics·Jhuma SankarSushil K Kabra
Mar 1, 2010·Pediatric Allergy, Immunology, and Pulmonology·R Paul Guillerman
Aug 24, 2010·Orphanet Journal of Rare Diseases·Annick ClementHarriet Corvol
Oct 16, 2013·Orphanet Journal of Rare Diseases·Jessica TaytardUNKNOWN French RespiRare® group
Jan 6, 2011·Journal of Postgraduate Medicine·S BhatiaK R Lahiri
Aug 3, 2013·American Journal of Respiratory and Critical Care Medicine·Geoffrey KurlandUNKNOWN American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network
Jun 15, 2014·Orphanet Journal of Rare Diseases·Laurent EnaudJacques de Blic
Mar 7, 2014·Pediatric Radiology·Laureline BertelootJacques de Blic
Mar 19, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Pilar García-PeñaGoya Enríquez
Sep 7, 2012·European Journal of Radiology·Luisa Lobo, Dulce Antunes
Oct 25, 2011·Paediatric Respiratory Reviews·Timothy J Vece, Leland L Fan
May 28, 2011·Pediatric Pulmonology·Frederik BuchvaldKim G Nielsen
Mar 30, 2016·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M FugerJ de Blic
Dec 18, 2013·Pediatric Pulmonology·C SileoH Ducou Le Pointe
Nov 1, 2016·Pediatric Pulmonology·Sureyya Burcu GorkemMehmet Köse
Oct 23, 2018·Expert Review of Respiratory Medicine·Nadia NathanAnnick Clement
Jun 30, 2009·Current Opinion in Pulmonary Medicine·Isham Huizar, Mani S Kavuru
Sep 15, 2009·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Maria Aparecida Soares de Souza Paiva, Sandra Mara Moreira Amaral
Dec 16, 2020·Children·Valentina Agnese FerraroSilvia Carraro
Apr 24, 2019·Revue des maladies respiratoires·T SoumagneJ C Dalphin
Jun 22, 2020·La Presse médicale·Nadia NathanAnnick Clement
Jul 29, 2009·Current Opinion in Pulmonary Medicine

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