Diagnostic value of neck node status using 18F-FDG PET for salivary duct carcinoma of the major salivary glands

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Ja Young KimSeung Do Ahn

Abstract

(18)F-FDG PET and PET/CT have shown clinical usefulness in the initial staging and follow-up of patients with salivary malignancy. Therefore, we evaluated the utility of (18)F-FDG PET in preoperative staging, determining the extent of neck node involvement, and surgical planning for patients with salivary duct carcinoma (SDC) of the major salivary gland. We evaluated 18 patients with SDC who were assessed by (18)F-FDG PET and CT before surgery. The sensitivity, specificity, accuracy, and predictive values of CT and PET/CT for predicting the primary tumor site and determining the extent of neck node involvement at each dissected neck level were evaluated by comparing imaging findings with pathologic nodal stage. The median maximum standardized uptake value of the primary lesions and cervical nodes were 4.7 (range, 1.8-12.1) and 5.8 (range, 1.7-13.0), respectively. The sensitivities of (18)F-FDG PET and CT for predicting the primary tumor site were 100% (18/18) and 94.4% (17/18), respectively. In analyzing cervical lymph nodes at 73 dissected neck levels, (18)F-FDG PET had a sensitivity of 76.1%, a specificity of 96.3%, a positive predictive value of 97.2%, and a negative predictive value of 70.3%; the corresponding values for CT...Continue Reading

References

Mar 1, 1991·Archives of Otolaryngology--head & Neck Surgery·W J KaneJ E Lewis
Sep 1, 1993·Cancer·R DelgadoJ Albores-Saavedra
Jul 1, 1994·Radiology·J W KeyesW F McGuirt
Jan 8, 1999·Acta Oto-laryngologica. Supplementum·T OkamuraY Nakai
Dec 10, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·A Sefik HosalEugene N Myers
Feb 22, 2005·Clinical Nuclear Medicine·Yoshitaka UchidaHisao Ito
Feb 1, 2006·Annals of Nuclear Medicine·Hideki OtsukaHiromu Nishitani
Jul 17, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Han-Sin JeongChung-Hwan Baek
Dec 31, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Young Hyeh KoHan-Sin Jeong

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Citations

Oct 17, 2014·Clinical Physiology and Functional Imaging·Pia AfzeliusKlaus Poulsen Bloch
Sep 30, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Giorgio TregliaLuca Giovanella
May 15, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Giovanni CammarotoUNKNOWN Young AIMN Working Group
Jul 24, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jae Won ChangEun Chang Choi
Apr 13, 2020·Medical & Biological Engineering & Computing·Javier Palacio-TorralbaYuhang Chen
May 19, 2019·Annals of Nuclear Medicine·Marie Westergaard-NielsenKristine Bjørndal

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