Diagnostic value of single-source dual-energy spectral computed tomography in differentiating parotid gland tumors: initial results

Quantitative Imaging in Medicine and Surgery
Lin LiWensheng Liu

Abstract

An accurate preoperative diagnosis that helps distinguish between benign and malignant parotid gland tumors is very important because the results strongly affect surgical procedures. We aimed to evaluate the value of single-source dual-energy computed tomography (ssDECT) in differentiating malignant from benign parotid gland tumors. Fifty patients underwent enhanced neck ssDECT scanning before surgery. The images were analyzed using the gemstone spectral imaging (GSI) viewer software. Fifty-two tumors (43 patients) were confirmed histopathologically, comprising of 12 pleomorphic adenomas (PAs), 24 Warthin tumors (WTs) (15 patients), and 16 malignant tumors (MTs). The iodine concentration (IC), normalized iodine concentration to common carotid artery (NICA) and slope value of the spectral curve (λHU) of the WTs were significantly higher than those of MTs and PAs (all P<0.05). The optimal IC, NICA and λHU thresholds for differentiating PAs from MTs were 0.91 mg/mL, 0.15 and 1.09, respectively, achieving sensitivities of 91.7%, 91.7% and 91.7%, specificities of 95.0%, 85.0% and 95.0%, and accuracies of 94.2%, 86.5% and 94.2%, respectively for distinguishing PAs from MTs. The optimal IC, NICA and λHU thresholds for distinguishing WTs...Continue Reading

Citations

Jun 11, 2019·Expert Review of Anticancer Therapy·Reza Forghani

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