Diagnostic yield of capsule endoscopy versus magnetic resonance enterography and small bowel contrast ultrasound in the evaluation of small bowel Crohn's disease: Systematic review and meta-analysis

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Uri KopylovAnastasios Koulaouzidis

Abstract

Capsule endoscopy (CE), magnetic resonance enterography (MRE) and small bowel (SB) intestinal contrast ultrasound (SICUS) are the modalities of choice for SB evaluation. This study aimed to compare the diagnostic yield (DY) of CE to MRE and SICUS in detection and monitoring of SB CD through meta-analysis of the available literature. We performed a systematic literature search for trials comparing the accuracy of CE, MRE and SICUS for detection of active SB inflammation in patients with suspected and/or established CD. Only prospective studies comparing CE with another additional diagnostic modality were included in the final analysis. Pooled odds ratios (ORs) for the DY of the three modalities were calculated. A total of 112 studies were retrieved; following selection, 13 studies were eligible for analysis. The DY of CE for detection of active SB CD was similar to that of MRE (10 studies, 400 patients, OR 1.17; 95% CI 0.83-1.67) and SICUS (5 studies, 142 patients, OR 0.88; 95% CI 0.51-1.53). The outcomes were similar for the subgroups of suspected versus established CD and adult versus pediatric patients. CE was superior to MRE for proximal SB CD (7 studies, 251 patients, OR 2.79; 95% CI 1.2-6.48); the difference vs SICUS was n...Continue Reading

Citations

Nov 29, 2017·Journal of Crohn's & Colitis·Eyal KlangUNKNOWN Israeli IBD research Nucleus [IIRN)
Mar 14, 2018·Therapeutic Advances in Gastroenterology·Artur NemethErvin Toth
Jul 25, 2017·Expert Review of Gastroenterology & Hepatology·Uri KopylovRami Eliakim
Apr 27, 2018·European Journal of Gastroenterology & Hepatology·Ioannis V MitselosDimitrios K Christodoulou
Jul 10, 2018·Journal of Crohn's & Colitis·Peter BossuytYoram Bouhnik
Aug 24, 2018·Journal of Crohn's & Colitis·Christian MaaserUNKNOWN European Crohn’s and Colitis Organisation [ECCO] and the European Society of Gastrointestinal and Abdominal Radiology [ESGAR
Mar 8, 2019·Current Opinion in Gastroenterology·Stefania Chetcuti ZammitReena Sidhu
Mar 5, 2020·Journal of Gastroenterology·Kento TakenakaKazuo Ohtsuka
May 13, 2020·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Alan LoboRhodri Saunders
Jul 7, 2020·Intestinal research·Ida Hilmi, Taku Kobayashi
Jun 13, 2018·Inflammatory Bowel Diseases·Dario Sorrentino, Vu Q Nguyen
Nov 7, 2018·World Journal of Clinical Cases·Elena Daniela Serban
Mar 9, 2019·Journal of Gastroenterology and Hepatology·Choon Jin OoiUNKNOWN Asia-Pacific Association of Gastroenterology (APAGE) Working Group on Inflammatory Bowel Disease and Asian Organization for
Mar 28, 2020·United European Gastroenterology Journal·Rami EliakimUri Kopylov
Feb 23, 2019·Expert Review of Gastroenterology & Hepatology·Michael VasilakakisDimitris K Iakovidis
Jan 27, 2020·Techniques in Coloproctology·G PellinoUNKNOWN the Italian Society of Colorectal Surgery (SICCR)
Feb 7, 2019·Digestive Diseases and Sciences·Yuan-Yuan LuoZhuan Liao
Mar 28, 2020·United European Gastroenterology Journal·Bella UngarDan Carter
Jan 27, 2021·Digestive Diseases and Sciences·Hisashi ShigaAtsushi Masamune
Jan 30, 2021·Inflammatory Bowel Diseases·Alexander R Robertson, Ian D Arnott
Sep 28, 2019·Journal of the Canadian Association of Gastroenterology·David O PrichardKevan Jacobson
Mar 2, 2021·Gastrointestinal Endoscopy·Joshua MelsonDavid R Lichtenstein
Jan 24, 2020·Journal of the Canadian Association of Gastroenterology·Thomas M GoodsallRobert V Bryant
May 14, 2021·Frontiers in Pharmacology·Francesca FerrettiGiovanni Maconi
May 21, 2021·Inflammatory Bowel Diseases·Elsa A van WassenaerBart G P Koot

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