Diagnostic yield of repeat CT-guided biopsy for suspected infectious spondylodiscitis

Skeletal Radiology
Gregory J CzuczmanF Joseph Simeone

Abstract

The purpose of this study was to examine the yield of repeat CT-guided biopsy in patients with suspected infectious spondylodiscitis following an initial biopsy with negative microbiology, and to identify factors associated with successful pathogen isolation. In this retrospective study, 21 patients (12 men, 9 women; mean age, 52, range, 12-84) were identified with clinically and radiologically suspected infectious spondylodiscitis who underwent repeat biopsy following negative cultures from an initial biopsy. The microbe yield as well as demographic, clinical, and laboratory findings were reviewed and statistical analysis was performed. Repeat CT-guided biopsy isolated a causative microbe in 3/21 patients (14.3%). Younger age (p = 0.021) was significantly associated with successful microbe isolation. All three cases of successful microbe isolation occurred in patients not exposed to antibiotics (3/9 patients) whereas no successful microbe isolation occurred in patients who received antibiotics (0/12 patients); however, this difference did not reach statistical significance (p = 0.062). Gender, duration of symptoms, white blood cell count, biopsy interval, and biopsy site were not significantly associated with microbe isolation...Continue Reading

References

Mar 21, 2002·Surgical Neurology·Jonathan A FriedmanMichael J Ebersold
Oct 7, 2004·Postgraduate Medical Journal·J J RankineR A Dickson
Mar 24, 2006·AJR. American Journal of Roentgenology·Sven C A MichelJuerg Hodler
Aug 1, 2006·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ali HassounCarol Singer
Mar 6, 2007·Joint, Bone, Spine : Revue Du Rhumatisme·Franck GradosPatrice Fardellone
May 23, 2007·AJR. American Journal of Roentgenology·Jim S WuAndrew H Haims
Mar 8, 2008·Journal of Clinical Pathology·D A EnochN M Brown
May 9, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Eugenio RimondiMario Mercuri
Aug 16, 2008·Clinical Orthopaedics and Related Research·Shih-Chieh YangYuan-Kun Tu
Dec 2, 2008·Clinical Rheumatology·Enrique Marco de LucasFernando Quintana
Mar 28, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Sung Hwan HongHeung Sik Kang
Mar 20, 2010·The New England Journal of Medicine·Werner Zimmerli
Sep 3, 2010·Journal of Clinical Microbiology·Christopher D Doern, Carey-Ann D Burnham
Oct 12, 2010·The Journal of Antimicrobial Chemotherapy·Theodore GouliourisNicholas M Brown
Mar 24, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jonas MarschallDavid K Warren
Jan 11, 2012·Antimicrobial Agents and Chemotherapy·Chung-Jong KimNam Joong Kim
Mar 27, 2012·Indian Journal of Orthopaedics·Somika SethiP Chopra
May 26, 2012·AJNR. American Journal of Neuroradiology·B J KimH S Kang
Sep 24, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G GrasL Bernard
Dec 7, 2013·BioMed Research International·María Eugenia PortilloAndrej Trampuz
Aug 1, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elie F Berbari Infectious Diseases Society of America
Dec 26, 2015·Clinical Radiology·V AgarwalW T Delfyett
Apr 16, 2016·The Korean Journal of Internal Medicine·Eun-Jeong JooKyong Ran Peck
Sep 9, 2017·AJNR. American Journal of Neuroradiology·A L McNamaraA Srinivasan

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Citations

Oct 28, 2019·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Tal AckermanNimrod Rahamimov
Jun 11, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lawrence A LaveryDane K Wukich
Dec 19, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Fardad T AfshariWilliam B Lo
Sep 10, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Gilles AvenelOlivier Vittecoq
Apr 20, 2020·Skeletal Radiology·Jad S HusseiniConnie Y Chang
Dec 19, 2020·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Emilie ChotardSébastien Ottaviani

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