Abstract
Spontaneous cough is a symptom with diffuse diagnostic significance for childhood asthma. Information on the interrelations between presence/frequency of cough and other symptoms of asthma are not available to the physician. Tracheal sounds were continuously recorded in the homes of 60 children with and 30 without asthma, at 72 and 24 h, respectively. Presence and frequency of cough and presence of wheeze were scored by trained examiners. Wheeze was used to indicate airway obstruction during hours when peak expiratory flow (PEF) values were not available. PEF and self-reported dyspnea were assessed every 4 h. Results showed that asthmatics coughed significantly more often than control subjects during exacerbations, but not during remission. The highest diagnostic sensitivity percentages of cough were 72% for wheeze and 69% for a reduction in PEF > 20%. However, the diagnostic specificity was poor, 41% for wheeze and 34% for a reduction in PEF > 20%. Cough and dyspnea were independent. Three children did not cough during exacerbations. Persistent, isolated cough was observed in two children. It was concluded that spontaneous cough is modestly predictive of asthmatic exacerbations, but not of a diagnosis of asthma or severity of ...Continue Reading
References
Mar 22, 1979·The New England Journal of Medicine·W M CorraoR S Irwin
Sep 1, 1992·Chest·R BeckI Mitchell
Jul 1, 1990·Clinical Science·F H Quirk, P W Jones
Jun 1, 1990·Thorax·R W Fuller, D M Jackson
Sep 1, 1985·Thorax·J C PounsfordK B Saunders
Apr 1, 1988·The Journal of Pediatrics·A AvitalS Godfrey
Jul 1, 1987·Clinical Allergy·C M SalomeA J Woolcock
Nov 1, 1986·The American Review of Respiratory Disease·R J HoppR G Townley
Oct 1, 1987·Archives of Disease in Childhood·A H ThomsonH Simpson
May 1, 1985·American Journal of Diseases of Children·P D SlyR Weymouth
Oct 1, 1984·Australian and New Zealand Journal of Medicine·G G GilesK Shaw
Jan 8, 1982·JAMA : the Journal of the American Medical Association·P J Hannaway, G D Hopper
Feb 1, 1995·Thorax·S RietveldW A Everaerd
Jun 1, 1994·Thorax·P C Deegan, W T McNicholas
May 1, 1994·Archives of Disease in Childhood·M R Taylor
Jan 1, 1994·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·W W StormsP Byer
Oct 1, 1993·Thorax·K P Jones
Sep 1, 1996·Chest·S Rietveld, E H Dooijes
Jun 1, 1996·Journal of Pediatric Psychology·S RietveldP J Prins
Citations
Sep 19, 2002·Medical Engineering & Physics·Annemie Van Hirtum, Daniel Berckmans
May 31, 2002·Thorax·J D LeuppiC M Salome
Oct 31, 2003·Thorax·A M LiA Bush
Oct 31, 2003·Thorax·J C de Jongste, M D Shields
May 4, 2006·Thorax·A M LiT F Fok
Oct 28, 2005·International Journal of Behavioral Medicine·S Rietveld, J F Brosschot
Aug 8, 2014·JMIR MHealth and UHealth·Hyekyun RheeEileen Fairbanks
May 21, 2013·Journal of Pediatric Nursing·Hyekyun RheeArlene Butz
Feb 12, 2000·Chest·S Rietveld, W Everaerd
Jan 13, 2009·Pediatric Clinics of North America·Craig Mellis
Jun 6, 2009·Pediatric Pulmonology·Daphna VilozniLea Bentur
May 9, 2001·IEEE Transactions on Bio-medical Engineering·P HarperG R Wodicka
Mar 6, 2003·IEEE Transactions on Bio-medical Engineering·V Paul HarperGeorge R Wodicka
Sep 23, 2006·Behaviour Research and Therapy·Simon Rietveld, Ilja van Beest
Jul 9, 2002·Pulmonary Pharmacology & Therapeutics·Anne B Chang, Peter G Gibson
Aug 11, 2000·Behaviour Research and Therapy·S RietveldW Everaerd
May 5, 1999·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S RietveldP J Prins
Oct 18, 2015·Journal of Medical Internet Research·Hyekyun RheeMark F Bocko
Jul 1, 1999·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·S RietveldE H Dooijes
Jul 17, 2001·Journal of Medical Engineering & Technology·F al HatibI K Daskalov