Diagrammatic analysis of the respiratory action of the diaphragm

Journal of Applied Physiology
Theodore A Wilson, André De Troyer

Abstract

During isolated phrenic nerve stimulation, the muscles of the diaphragm shorten by 40-50% of their optimal length, and the force in the muscle and transdiaphragmatic pressure (Pdi) depend on the final muscle length. The muscle shortening depends on the load imposed on the diaphragm by pleural and abdominal pressures during a particular maneuver. The mechanics of the interaction between the diaphragm and the load is well understood, but the force-length properties of the diaphragm are nonlinear, and an algebraic analysis of the interaction is clumsy. Here we describe a graphical analysis of the interaction. The variable muscle length is transformed into an equivalent variable, i.e., volume displaced by the diaphragm (Vdi), to obtain the characteristic line for the diaphragm, a graph of Pdi vs. Vdi for a given level of activation. The load is described by the same variables. Therefore, load lines can be drawn on the same graph, and the equilibrium point for the diaphragm is given by the intersection of the load line with the characteristic line of the diaphragm. Graphical analyses of the volume dependence of the respiratory effects of diaphragm and intercostal muscle activation and for the interaction between them are shown.

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Jul 15, 2006·The Journal of Physiology·André De Troyer, Dimitri Leduc
Aug 12, 2006·Journal of Applied Physiology·Aladin M BoriekTheodore A Wilson
Nov 11, 2006·Journal of Applied Physiology·Dimitri Leduc, André De Troyer
Dec 15, 2007·Journal of Applied Physiology·Dimitri LeducAndré De Troyer
Mar 7, 2009·Journal of Applied Physiology·André De Troyer, Theodore A Wilson
Oct 3, 2009·Journal of Applied Physiology·André De TroyerTheodore A Wilson

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Citations

Aug 2, 2014·Microscopy Research and Technique·Thais Borges LessaCarlos Eduardo Ambrósio
Apr 6, 2016·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Thais Borges LessaCarlos Eduardo Ambrósio
Aug 5, 2014·Medical Hypotheses·Naveen S KoturRitesh G Menezes
Feb 26, 2011·Journal of Applied Physiology·André De TroyerMatteo Cappello
May 8, 2010·Journal of Applied Physiology·André De TroyerPierre Alain Gevenois
Jul 17, 2012·Journal of Applied Physiology·André De TroyerPierre Alain Gevenois
Nov 1, 2015·American Journal of Physiology. Heart and Circulatory Physiology·Andrea MoriondoDaniela Negrini

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