PMID: 7387275Jun 1, 1980Paper

Dialysis symptoms and stabilization in long-term dialysis. Practical application of the CUSUM plot

Archives of Internal Medicine
A A RosaC M Kjellstrand


Six symptoms that occur during hemodialysis were investigated to determine their frequency and to define when a patient's condition becomes "stable." Three symptoms--nausea, hypotension, and muscle cramps--stabilized after 13 dialysis treatments (approximately one month). Two symptoms, hypertension and vomiting, stabilized after 17 and 20 dialyses, respectively. Headache showed little variation per dialysis. The changes in the frequency of these symptoms were detected through the use of the cumulative sum technique (CUSUM). This technique was found to be much more discriminating than the original data. Hemodialysis patients should not be considered "stable" for investigation of changes in techniques or therapy until after 1 1/2 months of dialysis. Even then, symptoms will be found during each dialysis.


Dec 11, 1984·International Journal of Technology Assessment in Health Care·T Halper
Mar 11, 1999·Acta Physiologica Scandinavica·P UusimaaM Ikäheimo
Mar 7, 2001·Kidney International·S Dheenan, W L Henrich
May 1, 1987·Kidney International·A K CheungA L Wayman
Apr 1, 1986·Kidney International·A K CheungL W Henderson
May 21, 2014·Nephrology·Chiz-Tzung ChangChiu-Ching Huang
Aug 3, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K A CagneyN R Powe
Jan 1, 1982·Clinical and Experimental Dialysis and Apheresis·C Charytan, B S Spinowitz

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