Diamond-Blackfan syndrome: lymphocyte-mediated suppression of erythropoiesis

Science
R HoffmanL R Wasserman

Abstract

Peripheral blood lymphocytes from six patients with congenital hypoplastic anemia suppressed erythroid cell formation by normal human bone marrow cells in response to erythropoietin in vitro. The results suggest that the anemia in these children has an immunologic basis.

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Related Concepts

Adrenal Cortex Hormones
Hypoplastic Anemia
Metazoa
Bone Marrow Cells
Cell Differentiation Process
Abnormal Red Blood Cell
Erythropoiesis
Erythropoietin
Cricetus
Lymphoid Cells

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