Diamorphine for pain relief in labour : a randomised controlled trial comparing intramuscular injection and patient-controlled analgesia

BJOG : an International Journal of Obstetrics and Gynaecology
Rhona J McInnesHarper Gilmour

Abstract

To compare the efficacy of diamorphine administered by a patient-controlled pump (patient-controlled analgesia) with intramuscular administration for pain relief in labour. Randomised controlled trial. The South Glasgow University Hospitals NHS Trust. Primigravidae and multigravidae in labour at term (37-42 weeks). Women were randomised in labour to the study (patient-controlled analgesia) or control group (intramuscular). Randomisation was achieved through a random permuted block design stratified by parity. Study group women were given a loading dose of 1.2 mg diamorphine intravenously and then attached to the pump. Control group women received intramuscular diamorphine as per hospital protocol. Participants were also given 3 mg of buccal Stemetil. Data were collected throughout labour and at six postnatal weeks. Analgesia requirements during labour and women's satisfaction with the method of pain relief. Women in the study group (patient-controlled analgesia) used significantly less diamorphine than women in the control group (intramuscular) but were significantly more likely to state that they were very dissatisfied with their use of diamorphine and were significantly more likely to opt out of the trial before the birth of ...Continue Reading

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Citations

Nov 6, 2007·International Journal of Obstetric Anesthesia·J P TuckeyM Y K Wee
Mar 18, 2016·The American Journal of Bioethics : AJOB·Michael H AndreaeRosamond Rhodes
Dec 3, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·M Y K WeeS Burnard
Jul 26, 2005·Peptides·Richard J Bodnar, Gad E Klein
Jun 6, 2018·The Cochrane Database of Systematic Reviews·Lesley A SmithAnna Cuthbert
Sep 9, 2010·The Cochrane Database of Systematic Reviews·Roz UllmanTherese Dowswell
Mar 23, 2021·Zeitschrift für Geburtshilfe und Neonatologie·Berenike SeilerDominique Singer

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