PMID: 10986594Sep 15, 2000Paper

Diastolic (dys-)function and electrophysiology

Cardiology Clinics
P KohlE White


Cross-talk between cardiac electrical and mechanical function is a bidirectional process: The origin and spread of electric excitation govern cardiac contraction and relaxation, while the mechanic environment provides feedback information to the heart's electric behavior. The latter tends to be unduly disregarded by the medical community. This article reviews experimental findings on the effects of diastolic mechanics on cardiac electrophysiology, and describes physiological correlates, clinical manifestations, and therapeutic utility of cardiac mechanic stimulation in humans.


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Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Natalia TrayanovaPeter Kohl

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