Diastolic function in children with Kawasaki disease

International Journal of Cardiology
Elif Seda Selamet TierneySteven D Colan

Abstract

Coronary artery dilation (CAD) and left ventricular systolic dysfunction are recognized complications of Kawasaki Disease (KD). Diastolic function assessed by echocardiography in the KD patient population and its interrelationship to the KD course, systolic dysfunction, and CAD is less well characterized. The purpose of this study was to determine whether diastolic function is impaired in KD patients and whether there are any clinical correlates. All KD patients with an echocardiogram recording of tissue Doppler velocities were included. Patients were analyzed based on CAD (Group I: patients who had CAD during their disease course; Group II: patients who never had CAD). In addition, we compared measures of diastolic function in patients with echocardiograms 0-30 days (n=35) and >30 days (n=72) post-IVIG treatment. 116 patients (80 males) were included (mean age, 7.7±6.7 years; mean time since KD onset, 4.0±5.6 years). Group I (41 patients, 36%), compared to Group II, had decreased E'(lateral) and longer mitral early deceleration time. E'(lateral) and E'(septal) were significantly decreased in patients 0-30 days vs. >30 days post-IVIG, whereas mitral early deceleration time was not significantly different. Our results demonstrat...Continue Reading

References

Dec 3, 2004·Pediatrics·Jane W NewburgerUNKNOWN Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American H
Feb 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Daiji TakeuchiMaya Fujiwara
Jun 20, 2007·Circulation·Brian W McCrindleUNKNOWN Pediatric Heart Network Investigators
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats

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Citations

Feb 22, 2012·Pediatric Cardiology·Hugo GravelDaniel Curnier
Sep 25, 2012·Pediatric Cardiology·Sol Ji NoLucy Youngmin Eun
Oct 19, 2012·Current Opinion in Cardiology·Lori B DanielsJane C Burns
Mar 15, 2012·Pediatrics International : Official Journal of the Japan Pediatric Society·Ariane McNeal-DavidsonNagib Dahdah
May 21, 2015·Pediatric Cardiology·Daniel PhadkePei-Ni Jone
Jul 23, 2011·International Journal of Cardiology·Yuichiro Z SatoJane C Burns
Jul 23, 2015·Iranian Journal of Pediatrics·Mohammad-Nasir HematianMasoumeh Lotfi-Tolkaldany
Sep 30, 2017·Journal of Korean Medical Science·Heeyoung LeeLucy Eun
Apr 10, 2018·Journal of cardiovascular ultrasound·Soo Jung KangHyo Jin Kim
Nov 7, 2017·International Journal of Rheumatic Diseases·Audrey Dionne, Nagib Dahdah
Feb 2, 2021·IJC Heart & Vasculature·Susan M DusenberyAndrew J Powell
Jul 31, 2021·Pediatrics·Christine A CaponeElizabeth Mitchell

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