Diastolic ventricular interaction in patients after atrial switch for transposition of the great arteries: a speckle tracking echocardiographic study

International Journal of Cardiology
Pak-Cheong ChowYiu-Fai Cheung

Abstract

We tested the hypothesis that diastolic ventricular interaction occurs after atrial switch operation for transposition of the great arteries (TGA) and that subpulmonary LV diastolic function is influenced by septal geometry. Twenty-nine patients (male 19) after atrial switch operation for TGA aged 20.8 ± 4.1 years and 27 healthy controls were studied. Two-dimensional longitudinal systolic strain, systolic (SRs), early diastolic (SRe), and late diastolic (SRa) strain rates of both ventricles were determined using speckle tracking echocardiography. Early diastolic trans-atrioventricular velocity (E) and myocardial early diastolic myocardial velocity (e) at the ventricular free wall-annular junction were measured. Geometry of the morphologic left ventricle was quantified by the diastolic eccentricity index (EI). In both systemic and subpulmonary ventricles, SRe and SRa were significantly lower and trans-atrioventricular E/e ratios higher in patients than controls (all p<0.001). In patients, RV SRe correlated with left ventricular (LV) SRe (r=0.49, p=0.008), and RV SRa correlated with LV SRa (r=0.46, p=0.01). Significant leftward shifting of the septum in patients was reflected by the greater LV EI (p<0.001). In patients, LV EI cor...Continue Reading

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Citations

Feb 24, 2012·International Journal of Cardiology·Matina Prapa, Konstantinos Dimopoulos
Dec 27, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Andreas P KalogeropoulosWendy M Book
Mar 22, 2014·Korean Circulation Journal·Yiu-Fai Cheung
Dec 25, 2019·Heart Failure Reviews·Sumeet S Vaikunth, George K Lui
Apr 5, 2020·Heart and Vessels·Lok-Yee LauYiu-Fai Cheung

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