PMID: 2508161Jan 1, 1989Paper

Diazepam induces a dissociation between explicit and implicit memory

Psychopharmacology
J M DanionL Singer

Abstract

The effects of 0.2 mg/kg orally administered diazepam and of a placebo on explicit memory, implicit and knowledge memory were assessed using a free recall task, a word-stem completion task and two category-generation tasks. Twenty four healthy volunteers took part in this double-blind study. Diazepam impaired explicit but not implicit memory. The drug also spared knowledge memory. Explicit memory was linked with the diazepam-induced sedation and with the self-rated affective load of to-be remembered words, but implicit memory was not. The diazepam-induced dissociation between explicit and implicit memory supports the notion of two distinct forms of memory and reproduced the dissociation observed in organic amnesia.

References

Jan 1, 1976·Neuropsychologia·D N Brooks, A D Baddeley
Jan 1, 1985·Annals of the New York Academy of Sciences·H Weingartner
Jun 27, 1986·Science·L R Squire
Jan 1, 1987·Psychopharmacology·P P Roy-ByrneH Weingartner
Jan 1, 1988·Psychopharmacology·G C PrestonS M Stahl
Jan 1, 1987·Annual Review of Psychology·M K Johnson, L Hasher
Nov 1, 1987·Pharmacology, Biochemistry, and Behavior·J C FangM M Ghoneim
Jan 1, 1987·The American Journal of Psychiatry·O M WolkowitzD W Hommer
Jan 1, 1985·Annals of the New York Academy of Sciences·D L Schacter
Jan 1, 1985·Annals of the New York Academy of Sciences·N J CohenS Corkin
Jan 1, 1986·Journal of Clinical and Experimental Neuropsychology·L L LightJ L Capps
Jan 1, 1985·Neuropsychologia·L S CermakL R Wolbarst
Nov 14, 1970·Nature·E K Warrington, L Weiskrantz
Aug 1, 1970·British Journal of Anaesthesia·P R ClarkeJ A Thornton
Jul 1, 1967·Psychological Bulletin·C N Cofer
Dec 1, 1980·British Journal of Anaesthesia·A C McKay, J W Dundee
Jan 1, 1984·Psychopharmacology·R G Lister, S E File
Jan 1, 1981·Psychopharmacology·E D CaineS Wehry
Jan 1, 1982·Psychopharmacology·L R HartleyJ Williamson
Jul 22, 1983·Science·H WeingartnerP R Martin
Dec 17, 1982·Science·P GrafP E Haden
Oct 1, 1982·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·A J Parkin

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Citations

Jan 1, 1992·Psychopharmacology·H J WeingartnerO Wolkowitz
Sep 1, 1995·Psychopharmacology·D N JohnsonD T George
May 1, 1995·Psychopharmacology·H J WeingartnerD Hommer
Nov 1, 1995·Psychopharmacology·H V CurranM Bernik
Jan 1, 1993·Psychopharmacology·H V CurranD Allen
Jan 1, 1991·Psychopharmacology·H V Curran
Sep 1, 1996·Psychopharmacology·P VidailhetD Grangé
Apr 6, 2004·Psychopharmacology·Daniel BeracocheaChristophe Pierard
Apr 15, 1992·Biological Psychiatry·T H KellyM W Fischman
Jun 8, 1995·Journal of Affective Disorders·J M DanionP Greth
Sep 1, 1994·Schizophrenia Research·A Gras-VincendonL Singer
Mar 27, 2001·Pharmacology, Biochemistry, and Behavior·A KrazemD Béracochéa
Apr 20, 1999·Pharmacology, Biochemistry, and Behavior·N Borde, D J Beracochea
Mar 17, 1999·Brain Research. Cognitive Brain Research·E HirshmanJ Arndt
Feb 10, 2000·Brain Research. Cognitive Brain Research·T H RammsayerD Groh
Feb 1, 1994·Psychological Medicine·N BazinA Féline
Mar 17, 2001·Bipolar Disorders·N A Levy, P G Janicak
Nov 1, 1990·The Journal of Psychology·J B Murray
Dec 31, 1997·Journal of Clinical and Experimental Neuropsychology·W J LombardiD T George
Apr 21, 2004·Behavioural Pharmacology·A CelerierD Beracochea
Feb 24, 1999·Alcoholism, Clinical and Experimental Research·M ZackC M MacLeod
Jan 24, 2012·Journal of Cognitive Neuroscience·Anouk M van LoonVictor A F Lamme
Nov 14, 2013·PloS One·Julia D I MeuweseVictor A F Lamme
Jul 1, 1994·Psychopharmacology·P VidailhetJ L Imbs
Jul 19, 2013·Cognitive Neuropsychiatry·Erica NeillMariah Kordzadze
Dec 10, 1999·Brain and Cognition·E HirshmanA Henzler
Apr 23, 2013·Current Biology : CB·Anouk M van LoonVictor A F Lamme
Jul 13, 2001·Vision Research·T BeckersA Giersch
Mar 9, 2002·Consciousness and Cognition·Marilyne Massin-KraussJean-Marie Danion

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