PMID: 7018169Jan 1, 1981Paper

Diazepam rectal solution for home treatment of acute seizures in children

Acta paediatrica Scandinavica
K Hoppu, P Santavuori

Abstract

To gain clinical experience of treating acute convulsions in children with diazepam rectal solution, 17 epileptic children with prolonged convulsions were treated at home. The drug was used 65 times. On 2/3 of all occasions the seizure was interrupted in less than 15 min. A starting dose of 0.5 mg/kg is recommended, with a maximum of 20 mg per single dose. One patient had respiratory difficulties, one dizziness and two skin reactions.

References

Mar 1, 1976·JAMA : the Journal of the American Medical Association·K A Arndt, H Jick
Oct 1, 1973·The American Journal of the Medical Sciences·D J Greenblatt, J Koch-Weser
Sep 1, 1973·Epilepsia·T R Browne, J K Penry
Oct 1, 1969·Archives of Disease in Childhood·S McMorris, P K McWilliam

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Citations

May 1, 1986·Indian Journal of Pediatrics·K Ramakrishnan, K Thomas
Oct 1, 1988·European Journal of Drug Metabolism and Pharmacokinetics·R H FuerstR Olson
Nov 1, 1987·Pediatric Neurology·N M Graves, R L Kriel
Nov 7, 1981·Lancet·W R McWhirterH Smith
Apr 2, 1998·The New England Journal of Medicine·D H Lowenstein, B K Alldredge
Jun 25, 1998·The New England Journal of Medicine·F E DreifussW E Bell
Jan 1, 1996·Archives of Disease in Childhood·F U KnudsenJ Andresen
Oct 15, 1998·Archives of Disease in Childhood·R C Tasker
Jun 29, 2013·Journal of Translational Medicine·Stephanie OhlraunMarkus Schuelke
Nov 1, 1996·Brain & Development·F U Knudsen
May 18, 2004·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·John M Pellock
Jan 22, 2000·Epilepsia·F U Knudsen
Apr 10, 2003·Mayo Clinic Proceedings·Edward M Manno
Feb 1, 1994·Annals of Emergency Medicine·R A Dieckmann
Sep 29, 2011·CNS Neuroscience & Therapeutics·Peter Wolf
Mar 1, 1989·The American Journal of Emergency Medicine·A AlbanoJ G Wiegenstein
Mar 1, 1990·The Journal of Emergency Medicine·R S Seigler
Jan 1, 1997·Current Problems in Pediatrics·P R Camfield, C S Camfield
Apr 25, 2015·Lancet Neurology·John P Betjemann, Daniel H Lowenstein
Sep 10, 2016·Epilepsy & Behavior : E&B·Sheryl R HautJohn Pellock
Feb 11, 1999·The Annals of Pharmacotherapy·M S Akinbi, T E Welty
Mar 1, 1993·JPEN. Journal of Parenteral and Enteral Nutrition·M A McFaddenD F Kirby
Jul 1, 1994·Journal of Child Neurology·R D Elterman
Apr 1, 1983·Annals of Neurology·P Dyken, N Krawiecki
Sep 28, 2004·Journal of Child Neurology·Jaana TyyneläSara E Mole
Jul 1, 1989·DICP : the Annals of Pharmacotherapy·N M GravesD J Ehresman
Dec 1, 1988·Annals of Tropical Paediatrics·R M Sykes, J A Okonofua

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