Aug 26, 2014

diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals

Paula TataruYun S Song


We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing single-nucleotide polymorphism-based IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM.

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  • Citations4


Mentioned in this Paper

Genetics, Population
Recombination, Genetic
Computer Programs and Programming
Genetic Polymorphism
Single Nucleotide Polymorphism
Population Spatial Distribution

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