May 12, 2014

diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals

BioRxiv : the Preprint Server for Biology
Paula TataruYun S. Song

Abstract

Summary: We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM. Availability : <http://sourceforge.net/p/dical-ibd> Contact : yss{at}eecs.berkeley.edu

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Genome
Tract
Genome Assembly Sequence
Recombination, Genetic
Genomics
Inflammatory Bowel Diseases
Simulation
Sense of Identity (Observable Entity)
Software Tools
Detection

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.