May 12, 2014

diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals

BioRxiv : the Preprint Server for Biology
Paula TataruYun S. Song


Summary: We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM. Availability : <> Contact : yss{at}

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Mentioned in this Paper

Genome Assembly Sequence
Recombination, Genetic
Inflammatory Bowel Diseases
Sense of Identity (Observable Entity)
Software Tools

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